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cancer chpt 16

QuestionAnswer
CA is what? an abnormal cellular growth, a DNA mutuation, which forms a clone & abnormally proliferates IGNORING GROWTH REGULATING SIGNALS IN THE ENVIRONMENT, they infiltrate tissues, get into the lymph & blood & METASTASIZW
According to cellular equilibrium, cellular proliferation= what? cell death
CA cells do not respond to intracellular regulating signals, and divide how? divide indiscriminately
At the time of mitosis, how many cells can CA cells produce? > 2 @ a time
what's the difference between the young and elderly in regards to cell growth? cells of the young are accelerated for growth, where as for the elderly it is only to meet body's demand
How does the body repair mutant cells? Apoptosis (cell suicide), a good thing
Do CA cells go through apoptosis? No
What do CA cells ignore? contact inhibition
what is hyperplasia benign; an increase in the # of cells in a tissue, usually during rapid growth (BPH, women who breastfeed)
what is Metaplasia? reversible, precancerous- when one type of matture cells turns into another type of cell (Barret's esophagus changes from one cell-type to another)
what is dysplasia? 1st stage CA/precancerous; bizarre cell growth resulting in cells w/different sizes, shapes & arrangement from cells of the same type of tissue (PAP smear is stage 1 & curable)
what is anaplasia? malignant, last stage CA; cells that lack normal characteristics & differ in shape/organization from cells of origin
what is neoplasia? can be benign; uncontrolled cell growth which follows no physiological demand
what are 2 types of genes which can be affected by mutations? 1)protooncogenes; normally promote normal cell responses for regular growth 2)tumor suppressor genes; suppress (unneccesary) growth
what does poorly differentiated mean? close to mother cell- bad
Created by: arsho453
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