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FNP~Oncology
| Question | Answer |
|---|---|
| Define leukemias... | CA of WBC's, bone marrow; increased production of abnormal immature WBC's in bone marrow>>>crowds out production of normal RBC's and plts |
| What are the 4 classifications of Leukemia... | ~Acute Non-Lymphomic Leukemia (ANL)/Acute Myelogenous Leukemia (AML) ~Acute Lymphotic Leukemia (ALL) ~Chronic Lymphocytic Leukemia (CLL)~Chronic Myelogenous (CML) |
| Which leukemia constitiutes for 80% of acute adult cases? | ANL/AML |
| Which leukemia is more difficult to cure in adults than children? | ALL (90% remission rate in children) |
| Whick leukemia is most common in adults? | CLL |
| Which leukemia occurs most often in adults over 40? | CML |
| Which leukemia often occurs in boty middle and old age? | CLL |
| Pancytopenia with circulatin blasts (immature cells)is the hallmark of which leukemia? | ALL (decreased RBC's, WBC's, Plts) |
| Which leukemia has a remission rate of 50-85%? | ANL/AML |
| Which leukemia has a median survival of 10 years? | CLL |
| Which leukemia has a median survival rate of 3-4 yrs? | CML |
| Which leukemia has a long term survival of ~40% | ANL/AML |
| Lymphocytosis is the hallmark of which leukemia? | CLL |
| Philadelphia chromosome in leukemic cells is the hallmark for which leukemia? | CML |
| s/sx's of leukemia (*most common) | ~*generalized lymphadenopathy ~*wt loss ~bone pain ~bruising/petechiae ~fatigue ~weakness ~fever ~aorexia |
| What might labs/dx results show in leukemia? | ~CBC with subnormal RBC's and neutrophils (CBC w/dif) ~elevated ESR ~refer if bone aspiration is required to confrim diagnosis of acute v. chronic |
| Management of leukemia... | REFER |
| What are lymphomas? | cancer of lymph nodes; suspect if lymph nodes >1cm without infection, if > or equal to 4-6 wks should be biopsied |
| How are lymphnodes diagnosed? | by bx of enlarged node and staging (4 stages) |
| What is considered "Stage I" | disease localized to a single lymph node or group |
| What is considered "Stage II" | more than one lymh node group involved; confined to one side of the diaphragm (above or below) |
| What is considered "Stage III" | lymph nodes or the spleen involved; occurs on both sides of the diaphragm (above & below) |
| What is considered "Stage IV" | liver or bone marrow involvement |
| Which is worse: Non-Hodgkin's or Hodgkin's | Non-Hodgkin's |
| Is Hodgkin's more common in males or females | males |
| What is the average age of Hodgkin's | 32yo |
| Non-Hodgkin's is the most common neoplasm between what ages? | 20-40yo |
| What is the common presentation of Non-Hodgkin's | lymphadenopathy |
| What is the common presentaion of Hodgkin's | cervical adenopathy that spreads in a predictable fashion along lymph node groups w/ wt loss |
| Why is Non-Hodgkin's worse than Hodgkin's? | ~less predictable pattern of spread ~advanced stage of the dz is usually apparent by the dimt of presenting to clinic |
| T/F: Reed-Sternberg cells differentiate "Hodgkin's" from Non-Hodgkin's | True |
| Management of Hodgkin's and Non-Hodgkin's... | ~radiation therapy (Stage 1 or 2 *lymphoma only) ~chemotherapy (> or equal to Stage 2) ~bone marrow transplant |
Created by:
KimmiNP
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