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STD study

STD study for patholoy

QuestionAnswer
GENITAL HERPES SYMPTOMS BURING AT SITE, PAINFUL VESICLES, FEVER, MUSCLE ACHE (MOST ARE ASYMPTOMATIC)
GENITAL Herpes IS WHAT TYPE OF VIRUS NEUTOTROPICS - GETS INTO NEURONS
Incubation Period of herpes 2-10 days
GENITAL WARTS symptoms benign multiple growths, genital or anorectal
Treatment of warts remove warts (topical (antimitotic agents) sx, cryotherapy
monitor for what type of CA in warts types 16/18
spyhliis (treponema pallidum) spread via: contact with lesions and via placenta
how does it spread? syphyillis microbe enters and distributes systemically via circulation and lymph
1st stage symptoms syphyillis local, painless chancre (non bleed), exposure sites labia, penis, groin. Heals in 3-12wks, regional adenopathy (swollen)
2nd stage symptoms of syphyillis 6-8 wks post infection, lasts up to 6mos, maculopapular rash on hands and soles, generalized lymphadenopathy, mucous membrane pathes, flat pupules, fever, malaise
what is the latent period in syphillis? in between 1st and 2nd stages, no obv. clnical signs
3rd stage symptoms of syphillis 1-35 yr after 1st infection if untx, irreversible damage to bone, joints, cvs, ns
treatment for syphillis penicillin
Chalmydia symptoms bacterial, 2-10 days incubation, asymto. in most case. Female: mucopurulent discharge, dysuria (inflammation of urethra), bleeding and pelvic pain (ascend. inflamm) Male: mild dysuria, white clear discharge, testes pain (scrotal inflamm. of epidymis)
Treatment for chlamydia doxycycline or azithromycin
Gonorrhea (Neiserria gonorrhoea) Gram - cocci Symptoms (local) Female - purulent discharge, late pelvic pain, dsyuria, genital irritation, pharyngeal infect (oral trans), conjuntivitis Male: urethral discharge, dysuria, pharyngeal infection, conjunctivitis
Systemic Symptoms of gonnorrhea bacteremia, arthritis-dermititis syndrome (joints affected by infn. septic arthritis)
AIDS targets what cell in the immune system? t helper
aids etiology and transmission unsafe sex, contaminated blood, maternal (utero, labor, lactation) occupational health workers
what 3 factors increases the risk of aids with a needlestick injury? depth, site, viral load
Patho of Aids - 3 phases what is the first phase? infection, window period and seroconversion (time it takes body to produce Ab against microbe) and window period (3mos), high viral load and decreased CD4 count (receptors for T cells)
second phase of aids is latent period - asymptomatic, destruction of lymphatic tissue, recurrent resp. infxn, fatigue
third phase of aids is overt AIDS - 10 yrs from hiv to aids, targets T helpers cells, macros, B cells, destroys immune system
diagnosis of aids lab tests and clinical progression, ELISA, western blot assay, PCR, CD4 counts and viral loads
what is ELISA test for AIDS? emzyme test measures AB against virus
what is western blot assay in aids? measures Ab against Ag( most specific)
Mnfts of Aids opportunistic infections, resp (TB and pneumonia)GI(many) NS (dementia, encephalopathy) and CA d/t low immune, Karposi's sarcoma, non-hodgins lymphoma, cervical
tx of aids anti-virals (antiretrovirals) work backwords making DNA from RNA
Created by: terriann
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