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DIT 2009 WK 11

Q&A from DIT emailed questions WK 11

How does the drug dose response curve change with the addition of a competitive antagonist shifts curve to the right (no change in Vmax), decreasing potency and increasing EC50
How does the drug dose response curve change with the addition of a Non-competitive antagonist shifts agonist curve downward (no change in potency), decreasing efficacy
"Clue cells" under the microscope are indicative of Gardnerella vaginalis
Treatment for Garnerella vaginalis Metronidazole
Vitamin deficiency responsible for Rickets and Osteomalacia D
Vitamin deficiency responsible for BeriBeri or Wernicke-Korsakoff B1
Vitamin deficiency responsible for macrocytic, megaloblastic anemia Folate and B12
Vitamin deficiency responsible for Scurvy C
Vitamin deficiency responsible for an increase in PT and PTT K
Vitamin deficiency responsible for night blindness and dry skin A
Vitamin deficiency responsible for chelosis and corneal vascularization B2
Rules of 2 associated with Meckel's diverticulum 2 in long, 2 feet from ileoccecal valve, 2% of pop, 1st 2 yrs of life, 2 types of epithelia (gastric and pancreatic)
Thalamic nuclei that relays stations for uditory sensation Medial geniculate nucleus (MGN)
Thalamic nuclei that relays stations for visual sensation Lateral geniculate nucleus (LGN)
Thalamic nuclei that relays stations for motor to the body Ventral anterior/lateral nuclei (VA & VL)
Thalamic nuclei that relays stations for facial sensation Ventral posterior nucleus, medial part (VPM) - via CN V
Thalamic nuclei that relays stations for body sensation Ventral posterior nucleus, lateral part (VPL)
Describe Eisenmenger's Syndrome Pulmonary resistance increase causing L-R shunt to reverse to R-L, causing late cyanosis
Mechanism of disease in Guillian-Barre Sx Inflammation and demyelination of peripheral nerves and motor fibers of ventral roots
Clinical findings in Guillian-Barre Sx Symmetric ascending muscle weakness beginning in distal lower extremities
Leading causes of death ages 15-24 Injuries, homicide, suicide, cancer, heart disease
Leading causes of death ages 25-64 Cancer, heart disease, injuries, suicide, stroke
Side effects of Amiodarone Pulmonary fibrosis, corneal desposits, hepatotoxicity, skin deposits resulting in photodermatitis, neurologic effects, constipation, cardiovascular effects (bradycardia, heart block, CHF), hypo/hyper-thyroidism
Positive symptoms of Schizophrenia Delusions, hallucinations, disorganized speech (loose associations), disorganized or catatonic behavior
Negative symptoms of Schizophrenia Flat affect, social w/drawal, lack of motivation, lack of speech (alogia) or thought, poor grooming
Two causes of Homocystinuria - Cystathionine synthase deficiency - Decreased affinity of cystathionine synthase for pyridoxal phosphate
Treatment for Cystathionine synthanse deficiency Decrease Methionine and increase Cystine, and increase B12 and Folate in diet
Treatment for decreased affinity of cystathionine synthase for pyridoxal phosphate Increase B6 in diet
Signs of Bacterial Endocarditis Fever, Roth's spots, Osler's nodes, Murmur, Janeway lesions, Anemia, Nail-bed hemorrhage, Emboli
Virus associated with councilman bodies Yellow Fever Virus (Flavivirus)
Virus associated with Koplik spots Rubeola Virus (Measles - Paramyxovirus)
Virus associated with meningitis, orchitis, parotitis Mumps Virus (Paramyxovirus)
Virus associated with negri bodies Rabies Virus
Virus associated with positive heterophil antibody EBV (Positive Monospot Test)
Virus associated with fever, cervical lymphadenopathy, and hepatosplenomegaly EBV
Name some 30S ribosomal subunit inhibitors -Aminoglycosides: streptomycin, gentamycin, tobramycin, amikacin (bactericidal) -Tetracyclines (bacteriostatic)
Name some 50S ribosomal subunit inhibitors Chloramphenicol, Clindamycin, Erythromycin, Lincomycin, Linezolid, Oxazolidione
What is the cause of Achalasia Failure of relaxation of LES due to loss of myenteric (Auerbach's) plexus
How is Achalasia diagnosed Barium swallow (bird's beak) or manometry (high resting pressure at LES w/ little or no decrease in pressure a/w swallowing)
Structures that arise from the Paramesonephric ducts Fallopian tubes, uterus, and upper 1/3 of vagina
Another name for Paramesonephric ducts Mullerian Duct
Drugs known for causing Diabetes Insipidus Lithium and Demeclocycline
Drugs used to treat Diabetes Insipidus Desmoprssin, hydrochlorothiazide, indomethacin, amiodarone
Ketone body that imparts a fruity odor to breath during ketoacidosis Acetyl acetate
Ketone body not detected by urine tests Acetate
Most common primary cardiac tumor in adults Myxomas
Most common primary cardiact tumor in children Rhabdomyomas
Created by: snezya24



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