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Adv. Bio Ch 8
The Cell Cycle Vocabulary Terms
| Question | Answer |
|---|---|
| G1 Phase | The first phase of the cell cycle starting just after offspring cells form. |
| G2 Phase | The second growth phase of the cell cycle beginning after DNA synthesis. |
| G0 Phase | A resting stage of the cell cycle in which DNA replication and cell division stop. |
| S Phase | Synthesis of DNA; the phase during of the cell cycle during which DNA in the form of chromosomes is duplicated. |
| M Phase | Mitosis; the phase of the cell cycle during which mitosis (nuclear division) occurs |
| Restriction Point | A point of not return in the cell cycle; once this point passes, a cell is committed to a full round of the cell cycle |
| Nuclear Division | The division of the cell's nucleus, as in mitosis and meiosis |
| Cytokinesis | The division of the cytoplasm of a cell after nuclear division |
| Pyrimidines | A nitrogen containing base having one ring of carbon and nitrogen; C & T |
| Purines | A nitrogen containing base having two rings of carbon and nitrogen; A & G |
| Helicase | An enzyme responsible for unzipping the DNA molecule by breaking the hydrogen bonds between the nitrogen containing bases during the replication process. |
| DNA Polymerase | An enzyme that catalyzes the synthesis of a new DNA strand using one of the original strands as a template |
| Leading Strand | The strand of DNA that is replicated sequentially from the 3' end to the 5' end |
| Lagging Strand | The strand of DNA that is replicated by creating Okazaki fragments that are attached together in the 3' to 5' direction |
| Mutation | A change in DNA |
| Excision Repair | a DNA repair process where enzymes remove a damaged portion of DNA, synthesize a replacement section in place, and attach it to the neighboring DNA segments |
| Chromatids | The replicated copies of a chromosome that are joined by a centromere and that separate during nuclear division. |
| Chromosome | Tightly coiled DNA and proteins |
| Chromatin | Loosely coiled DNA |
| Centromere | The specialized region of a chromosome that holds two replicated chromosomal strands together and that attaches to the spindle in mitosis. |
| Polar Fibers | A type of spindle fiber that extends from centrosome to centrosome in a dividing cell. |
| Kinetochore Fibers | A type of spindle fiber that extends from centrosome to the centromere of each chromosome in a dividing cell. |
| Cyclins | A group of proteins whose function is to regulate the progression of a cell through the cell cycle and whose concentrations rise and fall throughout the cell cycle. |
| Kinase | A type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates |
| Protooncogene | Gene that regulates cell division in eukaryotic cells; mutations in protooncogenes can produce oncogenes, genes having the potential to produce changes in cellular metabolism, leading to cancerous growth. |
| Tumor Suppressor | A gene that inhibits the growth of tumors; deletion or inactivation of such a gene can result in cancer |