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Pharm Ch. 16

Antiparkinsonian Drugs-NOT ON TEST!

QuestionAnswer
What is akinesisa? a reduction or absence of psychomotor activity that results in a masklike facial expression and impaired postural reflexes. Characteristics of parkinson's disease
What is bradykinesia? slowness of movement, symptom of parkinson's disease
What is Chorea? a condition characterized by involuntary, purposeless, rapid motions such as flexing and extending the fingers, raising and lowering the shoulders, and grimacing
What is dyskinesia? an impaired ability to execute voluntary movements
What is dystonia? impaired or distorted voluntary movement due to a disorder of muscle tone
What is exogenous? a term describing any substance produced outside of the body that may be taken into the body
What is on off phenomenon? a common experience of pt's taking medication for parkinson's disease in which they experience periods of greater symptomatic control alternation with periods of lesser control
What is parkinson's disease? a slowly progress, degenerative neurologic disorder characterized by resting tremor, pull rolling of the fingers, masklike facies, shuffling gait, forward flexion of the trunk, loss of postural reflexes, and muscle rigidity
What is postural instability? a decrease or change in motor and muscle movements that leads to unsteadiness and hesitation in movement and gait when the individual starts or stops walking
What is presynaptic? drugs that exert their antiparkinsonian effects before the nerve synapse
What is rigidity? resistance of the muscles to passive movement: leads to the cogwheel rigidity seen in parkinson's disease
What is tremor? in parkinson's shakiness of the extremities seen mostly at rest
What is wearing off phenomenon? a gradual worsening of parkinsonian symptoms as pt's medications begin to lose their effectiveness, despite maximal dosing with a variety of meds
What are the neurotransmission related abnormalities in parkinson's? progressive generation of dopamine producing neurons in the brain
What are drug therapies for parkinson's? dopamine agonists, MAOIs, anticholinergics, and COMT inhibiters
Which should alert the nurse to a potential caution or contraindication regarding the use of a dopaminergic drug for treatment of mild parkinson's disease? Angle closure glaucoma
A pt is taking entacapone as part of the therapy for parkinson's disease. which intervention by the nurse is appropriate at this time? Notify the pt that this drug causes discoloration of the urine
During a pt teaching session about antoparkinsonian drugs, the nurse will include which statement? Change positions slowly to prevent falling due to postural hypotension
A pt will be takin selegiline, 10 mg daily, in addition to dopamine replacement therapy for parkinson's disease. the nurse will implement which precautions regarding selegiline? Monitor for synocope or dizziness
A pt with parkinson's disease will start taking entacapone along with the carbidopa levodopa therapy he has been taking for a few years. the nurse recognizes that the advantage of taking entacapone is that? the entacapone can reduce on off effects
Created by: alicia.rennaker
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