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VIral Replication

Viral stuff_S3

where does the pox virus replicate in the cytoplasm. therefore has to bring its own DdDpol and DdRpol
gapped dsDNA hepadnavireidae (Hep B). first gapped is repaired and then transcriped into RNA and then a reverse transcriptase is made which made the gapped DNA again.
name a virus that replicates in the nucleus but brings its own DdDpol herpes
DdDPol vs. DdRpol DdDpol can read ssDNA but DdRpol cannot
what happens if the -RNA virus does not carry its own RdRpol the -RNA that the virus is carrying gets degraded when they penetrate the host. if the virus penetrates the cell carrying its own pol( which is usually complexed with the RNA), then the -ssRNA gets amplified via a +RNA intermediate
ribosomes recognize only ssRNA true
how are rate and specificity of viral assembly controlled individual subunits must be present in appropriate cellular compartments in sufficient concentration
packaging incorporation of the genomic nucleic acid into the protective structures
advantage of concerted or coordinated assembly instead of sequential no increase in structural subunit concentration is required since the units are incorporated as nucleic acid syn progresses.
release of naked viruses as a general rule, they are released by host cell lysis - possibly by increasing membrane permeability and/or weaken the cytoskeleton
which naked viruses dont exit by cell lysis Hep A, papillomavirus
sequential model of core formation and envelope acquisition eg: herpes virus
simultaneous model of core formation and envelope acquisition eg: retroviruses
viral maturation in orthomyxoviridae orthomyxoviridae is flue virus. involved cleaving of the sialic acid so the virus dont clump together. this increases their chance of infecting host cells.
Created by: kokila



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