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Endocrine ch13
| Question | Answer |
|---|---|
| Glands | Thyroid, Parathyroid, Adrenal Cortex & Medulla, Pancreas, Pituitary, Ovaries & Testes |
| Thyroid | Hormones: Thyroxine T4 & Triiodothyronine T3: made from iodine.increases metabolism in cells. normal growth & dev. & formation of nervous syst. Calcitonin: calcium goes into bone. lowers blood calcium. stimulates activity of osteoblasts. |
| Parathyroid gland | Hormone: Parathyroid hormone-increases blood calcium |
| Adrenal Cortex | Hormones: Cortisol (glucocorticoid)increases blood sugar. Aldosterone(mineralcorticoid) increases reabsorbtion of sodium. Androgen & Estrogen:sexual characteristics |
| Adrenal Medulla | Hormones: epinephrine (adrenaline) & norepinephrine (noradrenaline)both sympathomimetic=copying the effect of the sympathetic nervous system. |
| Pancreas | Exocrine cells secrete digestive enzymes into GI tract. Hormones:Insulin-decreases blood sugar(glucose to glycogen) glucose IN to cell. Glucagon-(glycogen to glucose)"glucose all gone" tells liver to make glucose by breaking down glycogen |
| Pituitary Anterior lobe | Hormones: Growth Hormone, ACTH, Follicle-Stimulating hormone, Luteinizing hormone, Thyroid-Stimulating hormone & Prolacting |
| Pituitary Posterior lobe | Hormones: Antidiuretic hormone(ADH) & Oxytocin |
| Ovaries | Hormones: Estrogen-promote development of ova & female secondary sex charachteristics. Progesterone: Prepares & maintains the uterus in pregnancy. |
| Testes | Hormone: Testosterone-promotes development of sperm & male secondary sex characteristics. |
| Steroid Hormones | React w/nucleus.Glucocorticoids(cortisol), mineralocorticoids(aldosterone), androgens(testosterone) + estrogen |
| Non Steroid Hormones | Cell surface receptors & messengers. norepinephrine & epinephrine |
| Steroid Hormone Action | cross cell membrane,receptor(in nucleus),complex binds to DNA & promotes transcription of mRNA, mRNA directs protein synthesis |
| Non Steroid Hormone Action | bind to receptor ON cell membrane, activates adenylate cyclase = ATP -> cAMP, cAMP promotes reactions: protein kinases activate substrates |
| Hyperthyroidism and Graves Disease | Hyper-high metabolic rate, sensitivity to heat, restlessness, weight loss, protruding eyes, goiter. Graves - auto immune. protrution of eye balls plus same as above. |
| Hypothyroid | Hashimoto disease-autoantibodies attack thyroid cells result in hypothyroidism. Cretinism(infancy) stunted growth, abnormal bone formation,retardation. Myxedema(adults)low metabolic rate, sensitivity to cold,poor appetite, slugish,swollen glands |
| Pineal gland | Hormone: Melatonin supports the body biological clock and induces sleep. (SAD) depression in winter months. |
| Thymus | Hormone: Thymosin - affects immune response. |
| Aldosterone(mineralocortidoid) | Regulates concentration of salt in body. Acts on kidney to reabsorb sodium and water and to excrete potassium. Thus, it regulates blood volume & pressure & electrolyte concentration. |
| Epinephrine (adrenaline) | Increases heart rate & blood pressure, dilates bronchial tubes, & releases glucose from glycogen when the body needs it for more energy. sympathomimetic, part of fight or flight reaction. |
| Norepinephrine (noradrenaline) | Constricts blood vessels to raise blood pressure. |
| T4 & T3 | Secreted by the Thyroid, increases metabolism in cells |
| Calcitonin | Secreted by Thyroid gland, lowers blood calcium |
| Parathyroid hormone | Parathyroid gland, increases blood calcium |
| Cortisol(glucocorticoid) | Secreted by Adrenal Cortex. Increases blood glucose. Inhibits the synthesis of protein, increasing blood concentration of amino acids. |
| Aldosterone(mineralcorticoid) | Secreted by Adrenal Cortex. Increases salt reabsorbtion |
| Insulin | Secreted by Pancreas. Lowers blood sugar (glucose to glycogen) |
| Glucagon | Secreted by Pancreas. Raises blood sugar (glycogen to glucose) |
| ACTH hormone | Secreted by Anterior Pituitary lobe. Stimulates adrenal cortex |
| Follicle-stimulating hormone | Secreted by Anterior Pituitary lobe. Stimulates ovaries and testes |
| Leuteinizing hormone | Secreted by Anterior Pituitary lobe. Promotes ovulation, stimulates testosterone secretion |
| Growth hormone | Secreted by Anterior Pituitary lobe. Stimulates growth of bones and soft tissue |
| Thyroid-stimulating hormone | Secreted by Anterior Pituitary lobe. Stimulates thyroid gland and T4 & T3 secretion |
| Prolactin | Secreted by Anterior Pituitary lobe. milk production. |
| Antidiuretic hormone | Secreted by Posterior Pituitary lobe. Increases water reabsorbtion. |
| Oxytocin | Secreted by Posterior Pituitary lobe. Stimulates labor and releases milk. |
| Estrogen | Secreted by Ovaries. Promote development of ova. |
| Progesterone | Secreted by Ovaries. Prepares and maintains the uterus in pregnancy. |
| Testosterone | Secreted by Testes. development of sperm |