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Micro/Pathology
Question | Answer |
---|---|
Pathology | study of diseases |
Etiology | study of disease causes |
Pathogenesis | how a disease will develop in time |
Infection | invasion of the body by pathogenic organisms |
Disease | when an infection results in a change in the state of health |
Normal flora | microorganisms that take up permanent residence and yet do not cause any disease |
Microbial antagonism | normal microbiota can benefit the host by preventing the overgrowth of harmful microorganisms |
Symbiosis | relationship between the normal microbiota and the host |
Commensalism | one organism is benefited and the other is unaffected; bacteria that eat skin that is sloughed off |
Mutualism | both organisms are benefited; E. coli in the large intestine synthesizes vitamins K and B |
Parasitism | one organism is benefited at the expense of the other; many diseases fit into this |
Synergism | both organisms must do their work together in order to be successful |
Pathogenic organisms | cause diseases |
True pathogens | routinely cause disease |
Opportunistic pathogens | under healthy conditions no effect, but will when other disease weakens the host |
Drug fast | antibiotic resistant (MRSA) |
Symptoms | subjective sick feelings not noticeable to others |
Signs | objective sick feelings measurable by others |
Syndrome | group of signs that always accompany a disease |
Communicable | able to spread from one to another |
Contagious | easily spread; influenza |
Non-communicable | not able to be spread to others; tetanus |
Incidence | fraction of the population who DEVELOP the disease in a time period |
Prevalence | fraction of the population who HAVE the disease in a time period |
Sporadic | happens occasionally; anthrax |
Endemic | constantly present in a population or area; common colds |
Epidemic | many people in a short time; influenza |
Pandemic | worldwide problem;or the majority of a population |
Acute | rapid appearance and lasting short time |
Chronic | slow appearance and lasts longer |
Latent | inactive for a period of time and then reactivates; chicken pox to shingles |
Local infection | located in a small area; boil |
Systemic infection or generalized infection | spread through the body through blood or lymph system; measles |
Focal infection | starts in one place and travels elsewhere; teeth to heart |
Bacteremia | presence of bacteria in the blood |
Septicemia | bacteria are now growing in the blood |
Viremia | virus present in the blood |
Sapremia | saprophytes present in the blood |
Toxemia | Toxins in the blood |
Primary infection | Caused by illness |
Secondary infection | side disease that follow the initial illness |
Subclinical infection | disease that does not cause any noticeable illness, asymptomatic; |
Exogenous infections | pathogens from outside the body |
Endogenous infections | pathogens from within the host |
Mixed infections | a multiple infection caused by 2 or more microorganisms |
Terminal infections | those that end in death (or end at the airport) |
Passive carrier | transmit for less than one year with no sign or symptom |
Active carriers | share disease while having the same signs and symptoms |
Convalescent carriers | recovering from clinical form of disease |
Chronic carriers | carry the disease for longer than 1 year usually with no sign or symptom of the disease |
Animal source or Zoonoses | diseases that occur primarily in wild and domestic animals and are transmitted to humans Through direct animal contact such as a brush or a bite Or, with contaminated excreta Or, with food or water they have contaminated Or, through the air from hides |
WHat does a disease need to be able to spread? | a way to move from host to host |
Physical | person to person by casual touching, kissing and sexual contact that produce STD or sexually transmitted diseases; can also be animal to person contact |
Droplet | happens when expelled during coughing, sneezing, laughing, talking, spitting |
Congenital | in the womb through placental transmission or during childbirth while in the birth canal |
Indirect | airborne or ingestion, contact with an object |
Fomites | bacteria on inanimate objects as drinking glasses, door knobs, syringes etc. |
Insect (anthropod) vectors – | mechanical (outside insect), biologically (insect bites) |
Forensic | deal with the causes of death that have legal and medical significance either civil or criminal; it is an unrestricted action in that everything needed to be done to determine cause and manner of death, whether or not the embalmer likes it |
Coroner | 21, not a felon, elected to a four year term, often funeral directors, not necessary to be a pathologist |
Medical Examiners | board certified pathologists that are appointed by the county board and can be fired by that same board |
Clinical | they treat patients usually in larger institutions; body fluids, secretions and excretions; especially blood and urine |
Cellular Pathology | Rudolf Virchow is the father of this study |
Basis | cellular changes during growth is the beginning of disease |
Gross Path | any observation made with the observation of the eye |
Microscopic Path | histo-pathology, the need for a microscope to see |
General Path | changes not specific to a system or to a part |
Special Path | changes specific to a system or to a part |
Pathological Anatomy | removal of tissue for study |
Clinical Pathology | laboratory tests on body fluids and secretions |
Physiological pathology | regarding the functions of the body |
Forensic or Medical legal pathology | medical in cooperation with legal issues |
Biopsies | tissues removed from living or dead bodies to be studied, determined and advice given in consequences |
Surgical | from living bodies |
Autopsy | from dead human bodies |
Forensic | not voluntary, legal authority, determines cause and manner of death for legal reasons |
Clinical | voluntary and not often done, it confirms the cause of death or poses another cause of death; can be limited to a various part of the body; contributes to medical understanding; can provide some peace of mind to the surviving family |
Role of FD in autopsy request – | neither discourage nor encourage; can advise it may add a few days to the waiting for funeralization; Confidential information not to be discussed unless with family or medical professionals. |
Health | sound body, mind and soul; opposite of disease which is an interruption in the harmony of the body, mind and soul; holistic approach |
Disease | any change in the structure of the function of the body as a result of injury to tissue |
Fulminating | particularly severe, sudden and often fatal |
Recurrent | alternating increase and decrease in the disease |
Intercurrent | another disease occurring simultaneous with others |
Idiopathic | the kind of disease is not presently known |
Occupational | as a result of a working environment; why OSHA exists |
Febrile | disease with a fever |
Intoxicating | State of being poisoned |
Suppuration | the process of pus (white blood cells surrounding bacteria) formation |
Non-suppuration | no process of forming pus |
Deficiency | disease from a lack of essential dietary ingredients such as vitamins, and minerals |
Lesions | structural changes produced in the tissues as a result of disease |
Syndrome | a group of symptoms or signs which usually appear together to indicate a particular disease |
Diagnosis | the identification of a disease as to its name |
Prognosis | a prediction of the probable outcome of a disease |
Remission | a let-up in the severity of the disease with diminish signs, yet still present |
Sequalae | remote or much later effects of the disease |
Exacerbation | sudden increase in the severity |
Complication | unfavorable condition which occurs as a result of having the disease |
Pathogenesis | the manner in which it develops |
Iatrogenic | disease caused by a physicians treatment |
Factors exciting disease | trauma, physical or chemical agents, infectious agents, deficiency, allergens |
Predisposing factors | age, gender, race, occupation, environment, emotion, economic status, heredity |
Anomalies | ANything other than normal |
Aplasia | absence of body part |
Hypoplasia | underdevelopment of body part |
Spina bifida | Defect in the walls of the lower spinal column |
Polydactilism | extra digits |
Hernia | organ poking therough the wall of a muscle |
Fistula | abnormal path through the tissue created by your body |
Cyst | abnormal fluid filled sac |
Turner's syndrome | 45 chromosomes |
Amelia | abscence of limb |
Phocomelia | proximal parts underdeveloped |
Cleft lip or pallet | failed closure of the lip or pallet |
Cystic fibrosis | Cells are prevented from releasing chloride resulting in a salt imbalance |