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Pregnancy

QuestionAnswer
The conceptus undergoes preembryonic development for about two weeks After fertilization, then embryonic development from weeks 3-8, then fetal development from week 9 to birth.
An oocyte is fertilizable for up to 24 hours, most sperm are viable within the female reproductive track for up to 48 Hours
Sperm must survive the hostile enviroment of the vagina and become capacitated
Hundreds of sperm must release their acrosomal enzymes to break down the eggs corona radiate and zona pellucida
To prevent polyspermy, when one egg binds to receptors on the egg it triggers the cortical reaction then the slow block to polyspermy
Following sperm penetration the secondary oocyte completes meiosis II then the ovum and sperm pronuclei fuse (fertilization), forming a zygote
Cleavage is a rapid series of miotic divisions without intervening growth, this begins with the zygote and ends with a blastocyte.
The blastocyte consists of the trophoblast and an inner cell mass
Cleavage produces a large number of cells with a favorable surface- to -volume ratio
The trophoblast adheres to, digests, and implants in the endometrium
Implantation is completed when then the blastocyst is entirely surrounded by endometrial tissue, about 14 days after ovulation
hCG released by the trophoblast (than later by the chorion) maintains the corpus luteum and therefore the corpus luteum keeps on producing estrogen and progesterone, preventing menses
Pregnancy tests use antibodies that detetect hCG in a womans blood or urine
After 2 to 3 months the placenta takes over the production of progesterone and estrogen form the corpus luteum. During this time hCG levels fall substantially and the corpus luteum
the placenta acts as the respiratory, nutritive, and excretory organ of the fetus and produces the hormones of pregnancy
the ectrembryonic mesoderm (formed from the inner cell mass) and the cytotrophblast make up the chorion
The chorion develops fingerlike chotionic villi, the cores of the chorionic villiwill eventually develeop into umbilical arteries and veins
The chorionoic villi lay in blood filles lacunae in the srtum functionalis layer of the endometrium
the part od the endometrium that lies between the chorionic villi and the sratum basalis (of the endometium) becomes the decidua basalis
the placenta is formed from the deciduas (maternal portion) and the chorionic villi (fetal portion)
Although the maternal and embryonic blood supplies are very close they normally do not intermix
The amnion protects the embryo from physical trauma, adhesion, formation, temperature swings, and allows fetal movements.
The yolk sac is the embryo's source of primordial germ cells and early blood cells
the allantois is an outpocketing of the yolk sac and is the stuctural basis for formation of the umbilical cord
Ectoderm forms the nervous system and the epidermis of the skin and its derivatives
Endoderm forms the mucosa of the digestive and respiratory systems, and all associated glands (thyroid, parathyroids, thymus, liver, pancreas).
Mesoderm forms all other tissues and organs that the ectoderm and endoderm do not form
The first event of organogenisis is neurulation, which produces the brain and spinal cord
The fetal cardiovascular system is formed during the the embryonic period
the umbilical vein delivers nutrient rich and oxygen rich blood to the embryo
the umbilical arteries deliver nutrient poor, waste laden, and oxygen poor blood to the placenta
The ductus venosus allows most of the blood to bypass the liver
The foramen ovale and ductus arterious are pulmonary shunts
maternal reproductive organs and breasts become increasingly vascularized during pregnancy and the breasts enlarge
the uterus eventually occuoies nearly the entire abdominopelvic cavity
Abdominal organs are pushed superiorly and encroach on the thoracic cavity
the increased abdominal mass changes the womens center of gravity. lordosis and backaches are common
A waddling gait occurs as pelvic ligaments and joints are loosened by placenta relaxin
A typical weight gain during pregnancy is about 28 pounds
Human placental lactogen has anabolic effects and promotes glucose sparing in the mother
Human chorionic thyotropin results in maternal hypermetabolism
Many women suffer morning sickness, heartburn, and constipation during pregnancy
During pregnancy, the kidneys produce more urine and pressure on the bladder may cause frequency, urgency, and stress incontinence
During pregnancy vital capacity and respiratory rate increase, but residual volume decreases dyspnea is common
During pregnancy total body water and blood volume increase dramatically, heart rate and blood pressure rise, resulting in enhanced cardiac output.
During late pregnancy estrogen levels become higher and induce oxytocin receptors on the myometrial cells and also inhibit progesterones quieting effect on uterine muscles. Weak irregular contractions begin.
During late pregnancy fetal cells produce oxytocin which stimulates prostaglandin production by the placenta
As birth nears oxytocin and prostaglandin stimulate contraction of the uterine muscle the increasinf stress activates the hypothalamus then releases oxytocin from the posterior pituitary, which causes positive feedback loop, resulting in true labor
the dialation stage is from the onset of rhythmic strong contractions until the cervix is fully dialated
the head of the fetus rotates as it decends through the pelvic outlet
The expulsion stage extends from full cervical dilation until birth of the infant
The placental stage is the delivery of the afterbirth ( the placenta and attached fetal membranes)
the infants apgar score indicates the infants physical condition and is recorded after the birth
After the imbilical cord is clamped carbon dioxide accumulates in the infants blood, causing respiratory centers in the brain to trigger the first inspiration
Once the lungs are inflated breathing is eased by the presence of surfactant, which decreases the surface tension of alveolar fluid
Inflation of the lungs causes pressure changes in the circulation causing the umbilical arteries and vein ductus venous and ductus arteriosis to collapse and closes the foramen ovale
the occuladed blood vessels are converted to fibrous cords the site of the foramen ovale becomes the fossa ovalis
the breasts are prepared for lactation during by high blood levels of strogen progesterone and placental lactogen
Colostrum a premilk fluid is a fat poor fluid that contains more protein , vitamen A, and minerals than true milk,, it is produced toward the end of the pregnancy and for the first two or three days after birth
True milk is produced around day three in response to suckling which stimulates the hypothalmus to prompt anterior pituitary release and posterior pituitary release of oxytocin.
Prlactin stimulates milk production oxytocin triggers milk let-down, continued breast feeding is required for continued milk production
At first ovulation and menses are absent or irregular during nursing,but in most women the ovarian cycle can eventually be reestablished while still nursing.
Created by: beck7815
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