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Trade Name Tyloenol, Tempra, Panadol, St Joseph, Valandol, Valorin
Class Clinically proven analgesic/antiipyetic. Produces analgesia by elevation of the pain threshold and antipyresis through action on the hypothalamic heat-regulating center. It’s an equivalent to ASA in analgesic and antipyetic effectiveness .Unlike ASA aceta
Onset Peak effect 1-2 hrs. Duration 3-4 hrs. Half-life 1-3 hrs.
Indication Substitute for ASA, when not tolerated or is contraindicated, to reduce fever and/or is temporarily relieve mild to moderate pain
Contraindications Not to be used continuously for > 10 day for adult or > 5 days in children, Hypersensitivity to drug or phenacetin, children< 3 yrs old unless directed by physician, Avoid repeated admin to patents with anemia pr hepatic disease. Use with caution in arth
Adverse Reactions Ac poisoning, hypoglycemia. CNS Dizziness, lethargy GI Anorexia N&V epigastric or abdominal pain diarrhea, hepatotoxicity, Hepatic coma, AC renal failure Other diaphoresis, chills
Drug Interactions Ch co-admin of barbiturates, carbanazepine,phenytoin, and rifampin may increase the potential for Ch hepatotoxicity or Ac acetaminophen overdose.
Admonistation Adult 325 – 650 mg PO q4-6 hrs with max 4g/daily. PR dose 650mg q4-6 w/max 4g/day Pediatric 15mg/kg q4- 6 hrs not to exceed 5 doses/ 24 hrs unless prescribed by physician
Created by: fsneumann