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Cell Bio UMKC
Exam 4
| Question | Answer |
|---|---|
| Which end of a microtubule is most likely to be found at the centrosome? A microtubule plus end B microtubule positive end C microtubule minus end D microtubule negative end | C microtubule minus end |
| Which term best characterizes the motility of a two-headed motor such as kinesin or dynein? A running B walking C hopping D gliding | B walking |
| Which of the following of dynactin helps dynein be a faster motor? dynactin can bind to both dynein & microtubules dynactin can bind 2 both microtubules & microfil dynactin can bind to dynein and intermediate filaments dynactin takes longer steps >dyn | |
| What molecule is added onto the growing end a microfilament? A actin monomer bound to GTP B actin monomer bound to ATP C actin monomer bound to ADP D actin dimer bound to ATP E actin dimer bound to ADP | A actin monomer bound to GTP |
| When Calcium ions are released from the sarcoplasmic reticulum, the ions bind directly to what molecule in order to stimulate muscle contraction? A Actin B Tropomyosin C Troponin D Myosin E Ras | |
| Cytoplasm from an egg cell in interphase is injected into a second egg cell in M phase. What happens? it undergoes apoptosis it dies by necrosis it stays in M phase forever it immediately stops M phase & enters interphase it continues thru M phase n | |
| What order do the following steps occur n the activation of cyclin dependent kinase (cdk)? 1 cdk starts positive feedback loop 2 cdk gets phosphorylated @ 2 locations 3 cdk binds to the correct cyclin 4 cdk has 1 of its phosphates removed by phosphat | |
| A cell is not able to progress through the cell cycle. Which of the following molecules can be phosphorylated in order to allow the cell to advance through the cell cycle? A retinoblastoma protein (Rb) B p53 protein C G1 cyclin D ras E telomerase | |
| What molecule is added to a cyclin to target that specific cyclin for degradation? A a phosphate B GTP C GDP D caspase E ubiquiti | |
| What role does p21 have n the cell cycle if DNA damage occurs? p21 causes transcription of p53 p21 degrades S-phase cyclin p21 phosphorylates S-phase CDK 2 inactivate CDK p21 binds 2 S-phase CDK 2 inactivate the CDK p21 inactivates ras 2 slow cell cy | |
| Which of the following molecules are cleaved specifically at the start of anaphase? A Anaphase promoting complex (APC) B S-phase CDK C Cohesins D Condensins E All of the molecules above are cleaved at the start of anaphase | |
| What prevents anaphase from occurring until all the chromosomes are aligned at the metaphase plate? A the DNA damage checkpoint B the spindle assembly checkpoint C the cell size checkpoint D caspases that inhibit APC | |
| Which would be considered proto-oncogene? p21 (no mutations) ras (no mutations) p21 with mutation present that inactivates p21 ras with mutation present that inactivates ras ras with mutation present that keeps ras activate constantly | ras (no mutations) |
| Once an apoptotic signal transduction cascade is activated, how is the signal turned off? A by anticaspases B by M-phase CDK C by caspases D by MAP kinase kinase E the signal cannot be turned off | |
| During what division does meiotic chromosomal recombination occur? A mitosis B meiosis I C meiosis II D mitosis and meiosis I E meiosis I and meiosis I | |
| During what division do bivalents align at the metaphase plate? A mitosis B meiosis I C meiosis II D mitosis and meiosis I E meiosis I and meiosis I |
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