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ATI PHARM unit 3

Chapter questions-meds affecting immune system

Which of the following situations is administration of a tetanus diphtheria(Td) booster indicated? Foot injury from stepping on a nail. Dog bite injury. Compound fracture. Last tetanus booster 12 yrs ago. (clean, incised, and scald injuries low risk for tetanus.)
What cautionary measures should be taken when immunizing individuals w/an MMR vaccine who have recently received a blood transfusion? MMR should be postponed 3-6 months. Immune globulins contain antibodies against viruses in MMR that inhibit the immune response to the vaccine.
which of the following meds has the ability to cause immunosuppression? Prednisone, Azathioprine, Cyclosporine, chemotherapy agts. It's important to take precautionary measures during therapy.
In which of the following situations is the administration of a dose of DTaP contraindicated? severe febrile illness, hx of prior anaphylactic reaction to DTaP vaccination, occurrence of seizures w/in 3 days of previous vaccination, occurrence of encephalopathy 7days after admin of DTaP immunization.
Why is it preferable to give the varicella vaccine in childhood rather than in adulthood? It protects children from getting the disease into adulthood. If adults get the disease it is likely to be severe.
What precautions should be taken for a clt who has just received a kidney transplant and is taking cyclosporine and phenytoin? Medications that decrease cyclosporine levels are phenytoin, phenobarbital, carbamazepine, rifampin, terbinafine, & trimethoprim-sulfamethoxazole. These can reduce cyclosporine levels & can lead to organ rejection. Increase cyclosporine dosage as needed.
What measures need to be taken to reduce development of osteoporosis during steroid therapy? Bone mineral density of the lumbar spine should be measured before starting therapy w/steroids. Glucocorticoids can be admin topically or by inhalation (less bone loss occurs). Several meds can be given to decrease bone loss.
Why is it important that children receiving the varicella vaccine avoid aspirin and salicylates for 6 weeks? Due to the risk of developing Reye's syndrome. increases with concurrent use of salicylates.
Created by: krislynn