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chapter 11

communication

QuestionAnswer
adenylyl caclase An enzyme that converts ATP to cyclic AMP in response to a chemical signal.
cyclic amp (cAMP) Cyclic adenosine monophosphate, a ring–shaped molecule made from ATP that is a common intracellular signaling molecule (second messenger) in eukaryotic cells
Diacylglycerol(DAG) A second messenger produced by the cleavage of a certain kind of phospholipid in the plasma membrane.
G Protein a GTP binding protein that relays signals from a membrane signal receptor to other signal transduction proteins inside the cell
G protien linked receptor A cell surface receptor that consists of a polypeptide chain threaded across the membrane seven times and that, when activated by the binding of a ligand, in turn activates a cytosolic G-protein molecule
Hormone In multicellular organisms, one of many types of circulating chemical signals that are formed in specialized cells, travel in body fluids, and act on specific target cells to change their functioning.
Inositol Trisphosphate (IP3) A second messenger that functions as an intermediate between certain nonsteroid hormones and a third messenger, a rise in cytoplasmic Ca 2+ concentration.
Ligand A molecule that binds specifically to a receptor site of another molecule.
Ligand-gated ion channels a protein pore in the plasma membrane that opensor closes in responce to a chemical signal, allowing or blocking the flow of specific ions
local regulator A chemical messenger that influences cells in the vicinity.
protein kinase An enzyme that transfers phosphate groups from ATP to a protein.
protein phosphate An enzyme that removes phosphate groups from proteins, often functioning to reverse the effect of a protein kinase.
Reception Reception is the target cell′s detection of a signal molecule coming from outside the cell. A chemical signal is “detected” when it binds to a receptor protein located at the cell′s surface or inside the cell.
Receptor tyrosine Kinase a protein in the membrane that responds to the to the binding of a signal molecule by catalyzing the trasnsfer of phosphate groups from ATP to tyrosines on the cytoplasmic side of the receptor
response In the third stage of cell signaling, the transduced signal finally triggers a specific cellular response. The response may be almost any imaginable cellular activity
scaffolding protein second messenger A type of large relay protein to which several other relay proteins are simultaneously attached to increase the efficiency of signal transduction.
signal transduction pathway A mechanism linking a mechanical or chemical stimulus to a specific cellular response.
transduction The binding of the signal molecule changes the receptor protein in some way, initiating the process of transduction. The transduction stage converts the signal to a form that can bring about a specific cellular response
Created by: leahfreeborn
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