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metha 2010 chp16

disorders associated with the immune system

QuestionAnswer
Hypersensitivity aka Allergy the immune system overreacts Type I Allergic Reactions
Hypersensitivity aka Allergy the immune system overreacts
Type I Allergic Reactions – Anaphylatic Occurs within 2 to 30 minutesIgE antibodiesbind to mastcellsreleasing histamineLocalizedhivesantihistaminesSystemicanaphylactic shockbreathing difficultiesepinephrine (EpiPen)-Food-related allergiesskin tests are not reliable and desensitiza
Type II Hypersensitivities - cytotoxic Transfusion reactions
Type III Hypersensitivities – Immune Complex ReactionsType IV Hypersensitivities – Cell-mediatedDelayed-type hypersensitivity allergic contact dermatitis
Autoimmune Hypersensitivity – Loss of the Immune System to Recognize SelfSeventy five percent selectively affect womenmay be hormone-related
Type I Autoimmunity antibodies that attack self-Rheumatic Fever – Streptococcus pyogenes and the heart
Type II Autoimmune Reactions – CytotoxicAntibodies attach to cell surfaces and interfere with normal body function.
Graves' disease thyroid cells
Myasthenia gravis to acetylcholine receptors and block nerve impulses
Type III Autoimmune Reactions – Immune Complex
Systemic lupus erythematosus Antibodies produced that are directed to cell components- even DNA
Rheumatoid arthritis Immune complexes deposited in the joints
Type IV Autoimmune Reactions – Cell-mediated involving T cells
Multiple sclerosis myelin sheath of nerves
Hashimoto's thyroiditis destruction of the thyroid gland by T cells
Insulin-dependent diabetes mellitustype I destruction of insulin-secreting cells of the pancreas by T cells
Immunodeficiency Diseases: Hyposensitivity of the Immune System
Primary Immunodeficiency Diseases – Genetic; Present at Birth
Secondary Immunodeficiency Diseases – Acquired Secondary acquired deficiencies in B-cells and T-cellsCauses. infection – HIVorganic diseasecancerchemotherapyimmunosuppressive drugsradiation
Created by: erjlkj
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