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Clopidogrel

QuestionAnswer
Type Potent inhibitor of platelet aggregation
Presentation Tablet – 75 mg
Action A specific and potent inhibitor of platelet aggregation: It does this by binding specifically and irreversibly to the platelet P2RY12 purinergic receptor, inhibiting ADP mediated platelet activation and aggregation Onset>30 minutes
Use Patients with an acute ST elevation myocardial infarction who meet the requirements for early percutaneous coronary intervention (PCI) procedure.
Adverse Effects 1. Headache 2. Dizziness 3. Stomach disturbances/pain 4. Diarrhoea or constipation
Contraindications 1. Known allergy 2. Known internal bleed within 6 months, 3. Current use of anticoagulants (excluding Aspirin or Clopidogrel),
Dose 8 x 75 mg tablets (600 mg) – taken orally Not to be dissolved but can be taken with water.
Created by: mattypepper