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PNS Pathology

Peripheral NS Pathologies

Anterior Horn Cell Sensory component intact
Anterior Horn Cell Motor weakness and atrophy
Anterior Horn Cell Fasciculation
Anterior Horn Cell Decreased DTR
Anterior Horn Cell Example: ALS, Polio
Peripheral Polyneuropathy Sensory impairments; "stocking glove" distributionq
Peripheral Polyneuropathy Motor weakness and atrophy; weaker distally than proximally; may have fasciculations
Peripheral Polyneuropathy Decreased DTR
Peripheral Polyneuropathy Example: diabetic peripheral neuropathy
Spinal Roots and Nerves Sensory component will have corresponding dermatomal deficits
Spinal Roots and Nerves Motor weakness in an innervated pattern; may have fasciculations
Spinal Roots and Nerves Decreased DTR
Spinal Roots and Nerves Example: herniated disc
Neuromuscular Junction Sensory component intact
Neuromuscular Junction Motor fatigue noted
Neuromuscular Junction Normal DTR
Neuromuscular Junction Example: myasthenia gravis
Peripheral Nerve (mononeuropathy) Sensory loss along the nerve route
Peripheral Nerve (mononeuropathy) Motor weakness and atrophy in a peripheral distribution; may have fasciculations
Peripheral Nerve (mononeuropathy) Example: trauma
Muscle Sensory component intact
Muscle Motor weakness; fasciculations are rare
Muscle Normal or decreased DTR
Muscle Example: muscular dystrophy
Created by: Hunter10