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PNS Pathology
Peripheral NS Pathologies
| Question | Answer |
|---|---|
| Anterior Horn Cell | Sensory component intact |
| Anterior Horn Cell | Motor weakness and atrophy |
| Anterior Horn Cell | Fasciculation |
| Anterior Horn Cell | Decreased DTR |
| Anterior Horn Cell | Example: ALS, Polio |
| Peripheral Polyneuropathy | Sensory impairments; "stocking glove" distributionq |
| Peripheral Polyneuropathy | Motor weakness and atrophy; weaker distally than proximally; may have fasciculations |
| Peripheral Polyneuropathy | Decreased DTR |
| Peripheral Polyneuropathy | Example: diabetic peripheral neuropathy |
| Spinal Roots and Nerves | Sensory component will have corresponding dermatomal deficits |
| Spinal Roots and Nerves | Motor weakness in an innervated pattern; may have fasciculations |
| Spinal Roots and Nerves | Decreased DTR |
| Spinal Roots and Nerves | Example: herniated disc |
| Neuromuscular Junction | Sensory component intact |
| Neuromuscular Junction | Motor fatigue noted |
| Neuromuscular Junction | Normal DTR |
| Neuromuscular Junction | Example: myasthenia gravis |
| Peripheral Nerve (mononeuropathy) | Sensory loss along the nerve route |
| Peripheral Nerve (mononeuropathy) | Motor weakness and atrophy in a peripheral distribution; may have fasciculations |
| Peripheral Nerve (mononeuropathy) | Example: trauma |
| Muscle | Sensory component intact |
| Muscle | Motor weakness; fasciculations are rare |
| Muscle | Normal or decreased DTR |
| Muscle | Example: muscular dystrophy |