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Step III
Step III - Renal 2
| Question | Answer |
|---|---|
| LOWER respiratory + renal presentation | Goodpastures |
| Cough, hemoptysis, SOB, lung findings + renal | Goodpastures |
| What is the best initial test for goodpastures | Anti-basement ABS |
| Most accurate test for goodpastures | Kidney bx w/ linear deposits |
| Tx for goodpastures | Plasmapheresis |
| Asthma, cough, EOSINOPHILIA + renal | Churg Strauss |
| What is the best initial tx for Churg Strauss | CBC showing EOSinophilia |
| Most accurate test for Churg Strauss | Bx |
| What is the best initial tx for Churg Strauss | Steroids |
| If initial tx for Churg Strauss does not work then tx | Cyclophosphamide |
| UPPER respiratory + LOWER respiratory + renal presentation | Wegener’s |
| SINUSITIS/OTITIS + hemoptysis, abnL CXR+ renal | Wegener’s |
| Crescentic, rapidly progressive/proliferative glomerulonephritis aka | Goodpastures |
| Hypersensitivity II in lungs PRIOR to kidney injury. IgG+C3 and LINEAR gbm | Goodpastures |
| What is seen on CXR in Goodpastures | B/L perihilar patchy infiltrates |
| Best initial test Wegener’s | c-ANCA + anti-proteinase-3 |
| Most accurate test Wegener’s | kidney bx |
| Best initial tx Wegener’s | cyclophosphamide and steroids |
| Name the two systemic vasculitis dz | PAN and Wegener’s |
| Which systemic vasculitis involves every organ but spares the lung | PAN |
| Multiple sensory and motor neuropathy + pain. Fever, weight loss, fatigue, uveitis, GI pain, myalgia, purpuric skin, stroke | PAN |
| Best initial test PAN | ESR OR inflammx markers |
| Most accurate test PAN | Bx sural n or kidney |
| Test that can be used to dx PAN sparing bx | Angiography showing beading |
| Best initial tx PAN | Cyclophosphamide + steroids |
| What dz is a/w PAN | Hep B/C |
| URI, LRI, Rhinitis, Hemoptysis | Wegener’s |
| Asian pt w/ recent viral respiratory infection presents w/ painless recurrent hematuria and nL complement levels. Nothing remarkable on PE | IgA/Berger’s Dz |
| Upper respiratory/GI + renal= | IgA/Berger’s |
| Best initial test IgA/Berger’s | nothing |
| Most accurate test IgA/Berger’s | renal bx |
| Best initial tx IgA/Berger’s | nothing effective; steroids / ACEI / fish oil |
| Child/adolescent c/o raised purpuric nontender pupuric skin lesions @ buttocks, ab pain, +/- bleeding, joint pain + renal | HSP |
| Best initial test HSP | Presentation of S/S |
| Most accurate test HSP and what does it show | Bx of kidney though rarely done; IgA deposits (don’t confuse with IgA/Berger’s) |
| Best initial tx HSP | Nothing resolves on own |
| Dark tea colored/cola colored urine, periorbital pain, HTN. h/o past infection = | Post streptococcal/post infectious glomerulo-it is |
| 10-14 days after ANY infection; IgG + C3 w/ granular, LUMPY, C3, Mild proteinuria, +/- ASO titer | Post streptococcal/post infectious glomerulo-it is |
Created by:
DrINFJ
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