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Neurotransmitters2
Overview of neurotransmitters S1
Question | Answer |
---|---|
Serotonin | (5HT) Emotion |
1st step of a neurotransmitter | Precursors from Diet---[sythesis]--->NT |
2nd step of a neurotransmitter | Neurotransmitter--[transport]-->vesicle package |
3rd step of a neurotransmitter | Vesicle Package--[action potential]-->Release |
final step of a neurotransmitter | Release--[Enzymatic, Reuptake]-->Deactivation |
Biogenic Amines | Dopamine Norepinephrine Serotonin Acetylcholine |
Peptide | Enkephalin |
Amino Amides | Glutamate GABA |
Nucleotide | Adenoside (Ade) |
Dopamine | (DA) motor systems |
Norepinephrine | (NE) sensory systems |
Acetylcholine | (Ach) neuromuscular junction |
Enkephalin | (Enk) pain |
Glutamate | (Glu) all over, almost always excitatory |
GABA | all over, inhibitory |
Adenoside | (Ade) |
Norepinephrine effects | controls sleep/wake cycle, effects Locus Coerueleus, Raphe Nucleus (Midbrain) |
Dopamine effects | (Midbrain, Amygdala) most addictions involve an increase of Dopamine in the Forebrain |
VMAT | 5HT binds to VMAT and is then pulled into the vesicle. |
Acetylcholine receptors | Muscarinic (G-protein, Ionotropic) and Nicotinic |
Histamine receptors | 3, all G-protein |