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Neurotransmitters2
Overview of neurotransmitters S1
| Question | Answer |
|---|---|
| Serotonin | (5HT) Emotion |
| 1st step of a neurotransmitter | Precursors from Diet---[sythesis]--->NT |
| 2nd step of a neurotransmitter | Neurotransmitter--[transport]-->vesicle package |
| 3rd step of a neurotransmitter | Vesicle Package--[action potential]-->Release |
| final step of a neurotransmitter | Release--[Enzymatic, Reuptake]-->Deactivation |
| Biogenic Amines | Dopamine Norepinephrine Serotonin Acetylcholine |
| Peptide | Enkephalin |
| Amino Amides | Glutamate GABA |
| Nucleotide | Adenoside (Ade) |
| Dopamine | (DA) motor systems |
| Norepinephrine | (NE) sensory systems |
| Acetylcholine | (Ach) neuromuscular junction |
| Enkephalin | (Enk) pain |
| Glutamate | (Glu) all over, almost always excitatory |
| GABA | all over, inhibitory |
| Adenoside | (Ade) |
| Norepinephrine effects | controls sleep/wake cycle, effects Locus Coerueleus, Raphe Nucleus (Midbrain) |
| Dopamine effects | (Midbrain, Amygdala) most addictions involve an increase of Dopamine in the Forebrain |
| VMAT | 5HT binds to VMAT and is then pulled into the vesicle. |
| Acetylcholine receptors | Muscarinic (G-protein, Ionotropic) and Nicotinic |
| Histamine receptors | 3, all G-protein |