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Diltiazem
Cardiac Pharmacology
| Question | Answer |
|---|---|
| What is the classification of Diltiazem? | Class IV Calcium Channel Blocker. |
| What are the pharmacodynamics of Diltiazem? | Slaws action potential of autorhythmic cells in the heart by blocking calcium channels. |
| What are the indications for the use of Diltiazem? | - First line medication for A-Fib and A-Flutter with RVR (Usually ventricular rates above 150 bpm) - Second line medication for SVT that is refractory to adenosine. |
| What are the contraindications of Diltiazem? | - Hypotension (Below 90 mmHg) - CHF/ Cardiogenic Shock - Wide Complex Tachycardia - WPW - Hypersensitivity to medication |
| What are the adverse effects of Diltiazem? | - Hypotension - Severe CHF may result if used along with Beta Blockers - Nausea/ Vomiting /Diarrhea - Dizziness - Headache |
| What is the dose for Diltiazem? | - First dose: 0.25 mg/kg with a max dose of 20 mg - Second dose: 0.35 mg/kg with to a max dose of 25 mg |