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Atropine

Cardiac Pharmacology

QuestionAnswer
What is the classification Atropine? Parasympatholytic
What is the pharmacodynamics of Atropine? Selectively blocks muscarinic receptors inhibiting the parasympathetic nervous system letting the sympathetic take over.
What are the indications of Atropine? - 1st line medication for symptomatic sinus bradycardia - May be beneficial in presence of AV nodal block - Organophosphate poisoning (very large doses required)
What are the contraindications of Atropine? - Allergic to drug - Use with caution in presence of myocardial ischemia & hypoxia causes increased myocardial O2 demand. - Avoid in hypothermic bradycardia - May not be effective for infranodal blocks be prepared to pace
What are the Adverse effects of Atropine? - Blurred vision - Dry mouth - Dilated pupils - Confusion - Doses <0.5 mg may result in paradoxical slowing of the heart
What is the dose of Atropine when dealing with bradycardia with or without ACS - 1 mg IV push every 3-5 minutes as needed, not to exceed total dose of 0.04 mg/kg (total 3 mg) - May use shorter dose interval (3 mins) in severe clinical conditions.
What is the dose for Atropine when dealing with organophosphate poisoning? - 2-4 mg (or higher) IVP
Created by: ejarami4
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