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Micro Chap 11

QuestionAnswer
Desiccation dehydration of vegetative cells when directly exposed to normal room air
Ionizing radiation radiation ejects orbital electrons from an atom causing ions to form
Non-ionizing radiation excites atoms by raising them to a higher energy state, but doesn't ionize them
alcohol mechanism of action? denature proteins (coagulation) and disrupts membranes by dissolving lipids
alcohol more effective against enveloped or non-enveloped viruses? enveloped
Phenolics able to act in presence of organic matter? YES
Phenolics mechanism of action? Disrupt cell walls, membranes, and precipitates proteins
Can phenolics be used as an antiseptic? No, too toxic
Tirclosan does what? targets the product of a specific gene, unusual effect on bacterial growth
Microbes are resistant to Tirclosan how? Drug efflux pumps, can be spread via conjugation
Can iodophors sterilize? Yes, with proper concentration/exposure times
Are iodophors adversely affected by organic matter and pH? NO
Can hydrogen peroxide sterilize? YES, at high concentrations
Is hydrogen peroxide an antiseptic or a disinfectant? Can be both, antiseptic in low concentrations
Fluorine, bromine, chlorine, and iodine are? Halogens
Halogens are? Microbicidal and sporicidal
Halogens mechanism of action? denatures proteins by interfering with both hydrogen and disulfide bonding
What's special about phenol? the first antiseptic used in surgery, now rarely used
Ag, Hg, and Cu Heavy metals, oligodynamic action
Heavy metals mechanism of action? dentaures proteins
Glutaraldehyde, formaldehyde, ethylene oxide, and chlorine dioxide are? alkylators
Alkylators mechanism of action? alkylate proteins and DNA
Created by: qclemenz
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