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Gina M White

HIV/AIDS Test #3

QuestionAnswer
How does HIV cause immune dysfunction? Destroying CD4 + T cells
When can immune problems start? When CD4 + T cell counts drop below 500 cells
What is CDC category A? (primary infection) #1 Symptoms=none to flu like Occurs 1-3 weeks after infection Rapid viral replication throughout body Viral set point = balance between amount of HIV and the immune response
What is CDC category A? (HIV Asymptomatic) #2 More than 500 CD4+ T lymphocytes viral set point reached sufficient immune response to defend against pathogens
What is CDC category B? (HIV Symptomatic) 200-499 CD4 + T lymphocytes pt develops conditions related to HIV infection that are not category c conditions: Oral hairy leukoplakia candida infection fever, sweats, diarrhea, headaches
What is CDC category C? (AIDS) less than 200 CD4 + lymphocytes as levels drop below 100, immune response is significantly impaired
What is the window period for the body to produce antibodies to HIV? 3 weeks to 6 months
OraSure quick, can be taken at home, looking for antibodies
Western Blot always repeated
When do patients need antiretroviral meds? T cell count less than 350
How often should T cell counts be measured? at diagnosis and every 3-6 months
How often should viral load testing occur? at diagnosis and every 3-4 months in the untreated person
Wasting syndrome 10% weight loss and chronic diarrhea or chronic weakness and fever
Wasting syndrome Protein energy malnutrition = muscle wasting
Kaposi's sarcoma cutaneous lesions but may involve multiple organ systems
cryptococcus neoformans fungal infection, fever, AMS, stiff neck, diagnose by spinal fluid analysis
Neuro disorder? AIDS dementia
Enema? cucumber extract
mycobacterium avium complex (MAC) resp infection, GI system, lymph nodes, bone marrow
Foods to avoid raw fruits and veggies, carbonated beverages, spicy foods, foods of extreme temperatures
Where do B lymphocytes mature? bone marrow
Where do T lymphocytes matures? thymus
What do lymph nodes serve as? a center for immune cell proliferation
Early clinical manifestations of RA Fatigue, loss of appetite, morning stiffness, widespread muscle aches, weakness
other manifestations of RA anemia, eye (burning, itching, discharge), limited ROM, pleurisy, nodules, numbness or tingling, paleness, skin redness or inflammation, swollen glands
Rheumatoid nodules High titers of RF, extensor surfaces of joints, nodules at base of spine and back of head, usually not removed
Sjogren Syndrome occurs as disease by itself or with other arthritic disorders, diminished lacrimal and salivary gland secretion (decreased tearing, photosensitivity)
Felty Syndrome inflammatory eye disorder, splenomegaly, lymphadenopathy, pulmonary disease, blood dyscrasias
Biological response modifiers Enbrel, Remicade, Humira, Kineret
Immunosuppressive agents Rheumatrex, Cytoxan, Imuran, Arava
Created by: gwhite09
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