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Gina M White
HIV/AIDS Test #3
| Question | Answer |
|---|---|
| How does HIV cause immune dysfunction? | Destroying CD4 + T cells |
| When can immune problems start? | When CD4 + T cell counts drop below 500 cells |
| What is CDC category A? (primary infection) #1 | Symptoms=none to flu like Occurs 1-3 weeks after infection Rapid viral replication throughout body Viral set point = balance between amount of HIV and the immune response |
| What is CDC category A? (HIV Asymptomatic) #2 | More than 500 CD4+ T lymphocytes viral set point reached sufficient immune response to defend against pathogens |
| What is CDC category B? (HIV Symptomatic) | 200-499 CD4 + T lymphocytes pt develops conditions related to HIV infection that are not category c conditions: Oral hairy leukoplakia candida infection fever, sweats, diarrhea, headaches |
| What is CDC category C? (AIDS) | less than 200 CD4 + lymphocytes as levels drop below 100, immune response is significantly impaired |
| What is the window period for the body to produce antibodies to HIV? | 3 weeks to 6 months |
| OraSure | quick, can be taken at home, looking for antibodies |
| Western Blot | always repeated |
| When do patients need antiretroviral meds? | T cell count less than 350 |
| How often should T cell counts be measured? | at diagnosis and every 3-6 months |
| How often should viral load testing occur? | at diagnosis and every 3-4 months in the untreated person |
| Wasting syndrome | 10% weight loss and chronic diarrhea or chronic weakness and fever |
| Wasting syndrome | Protein energy malnutrition = muscle wasting |
| Kaposi's sarcoma | cutaneous lesions but may involve multiple organ systems |
| cryptococcus neoformans | fungal infection, fever, AMS, stiff neck, diagnose by spinal fluid analysis |
| Neuro disorder? | AIDS dementia |
| Enema? | cucumber extract |
| mycobacterium avium complex (MAC) | resp infection, GI system, lymph nodes, bone marrow |
| Foods to avoid | raw fruits and veggies, carbonated beverages, spicy foods, foods of extreme temperatures |
| Where do B lymphocytes mature? | bone marrow |
| Where do T lymphocytes matures? | thymus |
| What do lymph nodes serve as? | a center for immune cell proliferation |
| Early clinical manifestations of RA | Fatigue, loss of appetite, morning stiffness, widespread muscle aches, weakness |
| other manifestations of RA | anemia, eye (burning, itching, discharge), limited ROM, pleurisy, nodules, numbness or tingling, paleness, skin redness or inflammation, swollen glands |
| Rheumatoid nodules | High titers of RF, extensor surfaces of joints, nodules at base of spine and back of head, usually not removed |
| Sjogren Syndrome | occurs as disease by itself or with other arthritic disorders, diminished lacrimal and salivary gland secretion (decreased tearing, photosensitivity) |
| Felty Syndrome | inflammatory eye disorder, splenomegaly, lymphadenopathy, pulmonary disease, blood dyscrasias |
| Biological response modifiers | Enbrel, Remicade, Humira, Kineret |
| Immunosuppressive agents | Rheumatrex, Cytoxan, Imuran, Arava |