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Antipsychotic Meds
Mental Health
| Question | Answer |
|---|---|
| chlorpromazine (Thorazine) | Traditional/Typical Antipsychotic |
| fluphenazine (Prolaxin) | Traditional/Typical Antipsychotic |
| haloperidol (Haldol) | Traditional/Typical Antipsychotic |
| thioridazine (Mellaril) | Traditional/Typical Antipsychotic |
| thiothixene (Navane) | Traditional/Typical Antipsychotic |
| Traditional/Typical Antipsychotic MOA | target dopamine 2 receptors, acting as antagonist to reduce dopamine activity in the brain. |
| Traditional/Typical Antipsychotic Treatment | used to treat disorders such as schizophrenia characterized by psychosis with agitation. (postive symptoms). Hallucinations, delusions, disorganized thoughts. |
| Traditional/Typical Antipsychotic SE | EPS Dystonia, dyskinesia, akathesia, tardive dyskinesia |
| Neuroleptic Malignant Syndrome | potentially fatal. Symptoms of high fever, muscle rigidity, autonomic instability, diaphoresis, pale skin, delirium,inability to speak, tremors, elevated enzyme= muscle damage |
| Endocrine SE | dopamine inhibit the hormone prolactin which promotes breast inlargement (gynomastia) which produces milk production (galactorrhea). Chronic prolactin elevation can cause decreased labido, irregular mestration, hyperglycemia dm type 2 |
| clonzapine (Clozaril) | Atypical Antipsychotics |
| olanzapine (Zyprexal) | Atypical Antipsychotics |
| quertidpine (Seroquel) | Atypical Antipsychotics |
| ziprasidone (Geodon) | Atypical Antipsychotics |
| Atypical Antipsychotics Action | influence a variety of dopamine receptor sites, serotonin recptors, muscarinic recpetors, alpha-receptors and histamine recpetors. |
| Atypical Antipsychotics treatment | Negative effects of schizophrenia, decreased dopamine activity. CAUSE FEWER EPS SE |
| Atypical Antipsychotics SE | weight gain, prolonged QT conduction time, DM, agranulocytosis (clonzapine) |
| Agranulocytosis symptoms | fever, sore throat, bruising, petichiae, increased bleeding, decreased caloric intake |
| benztropine (Cogentin) | Anticholinergic Drugs |
| biperiden(Akineton) | Anticholinergic Drugs |
| diphenhydramine (Benadryl) | Anticholinergic Drugs |
| procyclidine (Kemadrin) | Anticholinergic Drugs |
| trihexyphenidyl (Artane) | Anticholinergic Drugs |
| Anticholinergic Drugs MOA | competively inhibit action of aacetylcholine |
| Anticholinergic Drugs treatment | reduces rigidity and tremors counteracts cholinergic effects. |
| Anticholinergic Drugs SE | Dry mouth, constipation, pupil dialation (mydriasis), phototsensitity, orthostatic hypotension, urinary hesitancy/urgency, blurred near vision, increased HR. |
| aripiprazole (Abilify) | New Generation Antipsychotic |
| New Generation Antipsychotic MOA | Dopamine system stabilizer. Has a stabilizing and modulating effect on brain dopamine. |
| New Generation Antipsychotic Note | Does not cause EPS |
| Depot Injections | Long acting, every 2 weeks or 1 time monthly. Increases rate of complience with medications. |
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