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Honors DNA Technolog
| Term | Definition |
|---|---|
| Gel Electrophoresis | electric current to separate charged molecules like DNA, RNA, and proteins through a gel, based on their size and electrical charge. |
| Gene Therapy | Replacing an abnormal gene with a working copy of the gene, provides temporary treatment |
| Human Genome Project | goal to map all the human genes on all of the chromosomes |
| DNA cloning | many identical genes are produced |
| Genome | an organism's collection of genes |
| Goals of GMO's | pest and herbicide resistance, make more nutritious, bigger yield, stop world hunger |
| Recombinant DNA (rDNA) | formed by joining DNA molecules from two different sources |
| Cloning by Nuclear Transfer | enucleated donor egg and diploid donor nucleus are fused together producing an embryo that is implanted into a surrogate |
| % of genome identical between persons | 99.9% |
| length polymorphism | Variations in the length of the DNA molecule between genes |
| VNTR | variable number tandem repeats; DNA markers used in DNA profiling |
| STR | short tandem repeats; DNA markers used in DNA profiling |
| DNA vector | bacterial, viral or yeast yeast DNA that transport of DNA sequence into a nucleus & then replicate |
| Preimplantation Genetic Diagnosis (PGD) | Genetic testing on embryos for genes that cause untreatable or severe diseases. |
| Gene Editing | The ability to cut out and replace genes. Uses CRISPR |
| Embryonic Stem Cells | An undifferentiated cell, taken from an embryo that can become any other type of cell and divide indefinitely |
| Adult Stem Cells | undifferentiated cells from an adult that can form a few types of cells but have limited mitotic ability |
| Pluripotent | can form any type of cell |
| Multipotent | can form a few types of cells |
| Theraputic Cloning | cloning of stem cells for research |
| Reproductive Cloning | technology that produces genetically identical individuals |
| DNA Vaccines | vaccine that contains DNA of the pathogen but not its disease causing ability |
| Bioethics | the study of ethical issues related to DNA technology |