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cell theory
Biology
| Question | Answer |
|---|---|
| Cell Membrane Basics Why can only certain molecules cross the cell membrane easily? | The membrane is made of amphipathic phospholipids with hydrophobic interiors, so only small, non‑polar molecules pass easily; large or charged molecules require membrane proteins. |
| Simple Diffusion What is simple diffusion? | Movement of molecules from high concentration to low concentration |
| Does simple diffusion require ATP? | No. |
| Does simple diffusion require membrane proteins? | No |
| Give examples of molecules that use simple diffusion. | O₂, CO₂, N₂, glycerol, short‑chain fatty acids. |
| Factors Affecting Diffusion Rate How does increasing the concentration gradient affect diffusion rate? | Increases it. |
| How does increasing temperature affect diffusion rate? | Increases it. |
| How does increasing membrane surface area affect diffusion rate? | Increases it. |
| How does increasing diffusion distance affect diffusion rate? | Decreases it. |
| Osmosis What is osmosis? | Movement of water from high water concentration to low water concentration; no ATP required. |
| How can water cross the membrane? | It diffuses directly (small size) or through aquaporins. |
| What is a solute? | A substance dissolved in a solvent. |
| What is a solvent? | The liquid that dissolves the solute (e.g., water). |
| What is the typical osmotic concentration of a cell? | ~300 mOsmol. |
| What is the typical NaCl concentration in cells? | 0.9% (normal saline). |
| Tonicity What is a hypertonic solution? | Higher solute concentration than the cell. |
| What happens to a cell in a hypertonic solution? | Water leaves the cell; the cell shrinks. |
| What is an isotonic solution? | Same solute concentration as the cell. |
| What happens to a cell in an isotonic solution? | Water moves equally; the cell stays the same |
| What is a hypotonic solution? | Lower solute concentration than the cell. |
| What happens to a cell in a hypotonic solution? | Water enters the cell; it swells and may burst. |
| Facilitated Diffusion What does facilitated diffusion require? | Membrane proteins |
| Does facilitated diffusion require ATP? | No |
| Do molecules move down or against their gradient in facilitated diffusion? | Down their gradient. |
| What do channel proteins transport? | Ions |
| What do carrier proteins transport? | Nutrients like glucose and amino acids; can also move ions. |
| Can carrier proteins become saturated? | Yes |
| Where are major ions concentrated? | Sodium: higher outside Chloride: higher outside Potassium: higher inside Calcium: higher inside the smooth ER |
| Primary Active Transport Does primary active transport require ATP? | Yes. |
| Do molecules move down or against their gradient? | Against their gradient. |
| What does the Na⁺/K⁺ pump do? | Pumps 3 Na⁺ out and 2 K⁺ into the cell using ATP. |
| Why is the Na⁺/K⁺ pump important? | Maintains electrical gradient (inside more negative) Maintains chemical gradient (high Na⁺ outside for secondary transport) |
| What does the proton pump do? | Pumps protons across membranes (e.g., mitochondria) to create a gradient used to generate ATP via chemiosmosis. |
| Coupled Transport What is symport? | Two substances move in the same direction. |
| What is antiport? | Two substances move in opposite directions. |
| What is secondary active transport? | Uses the sodium gradient (not ATP directly) to pull nutrients like glucose or amino acids into the cell. |
| Movement of Large Molecules How are bulky substances moved across membranes? | Using vesicles. |
| What is endocytosis? | Engulfing substances into the cell via vesicles |
| What is phagocytosis? | Engulfing solids (e.g., immune cells engulfing pathogens). |
| What is pinocytosis? | Engulfing fluids (e.g., human egg taking in nutrient-rich fluid). |
| What is exocytosis? | Releasing substances from vesicles to the outside of the cell. |