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Week 3
Mendelian inheritance
| Question | Answer |
|---|---|
| Explain the biological significance of inheritance | Inheiritance is where genetic differences among individuals/passing of traits are passed from generation to generation. its important to maintain genetic stability but also genetic variation |
| What are the implications of inheiritance to the individual and to the evolution of the species? | Individual: traits + physical traits the organism will have, favorable traits will allow individual to survive better + reproduce more species: natural selection/evolution, accumulation of favorable traits suited to enviroment |
| What expirimental model did Mendel use + what were the advantages of the model? | He used pea plants becuase they were inexpensive, easy to grow, produced many seeds, had several polymorphic traits, + he could control which parents were involved in a mating |
| Describe examples of the characters + traits studied by Mendel | Seed shape, seed color, pod shape, pod color, flower color, flower + pod position, + stem length |
| What are examples of the true breeding plants that Mendel used + why was it important to start with true breeding plants? | Pea plants. It was important becuase true breeding = homozygus = traits were consistant and controlable and it let him see which traits were dominant or recessive |
| What methods did Mendel use to preform cross-pollination in pea plants? | Would cut off the male organs of the flower to prevent self pollination, then would manually fertilize the flowers using the specific plants that he wanted |
| What evidence did Mendel's expiriments provide to show that male + female plants contributed equally to offspring? | Traits are inheirited through paired alleles not by the gender of the specific parent |
| How is the "particulate" hypothesis supported + not the "blended" one by a comparison of phenotypes? | Traits did not blend as they were passed down. They act as discrete unchanging particles. |
| Can you always predict the ghenotype based on phenotype? | No. Becuase of dominant traits, you dont know if a genotype is heterozygous (AA) or homozygous (Aa) based on the phenotype |
| Define law of segregation | The 2 alleles of each gene pair must segregate. They seperate into differernt gamete cells during the formation of eggs and sperm in the parents |
| How did Mendel explain the re-emergence of white flowers in the F2 generation? | Law of segregation! The white flowers were a recessive trait, and the purple was dominant so white only had a chance to appear in the F2 generation, not the F1 one. |
| What is a testcross for? | A genetic test to determine the unknown genotype of an organism with a genotype (wether it's AA or Aa etc.) Crosses dominant genotype with a recessive genotype |
| Dominant vs. recessively inherited disorders | Dominant disorders will occur when only 1 allele is present from either parent, and resessive disorders require copies from both parents. Dominant typically appear in every generation and resessive will "skip" generations |
| Law of independent assortment | Alleles on non-homologous chromosomes assort independently during formation (alleles of one trait do not effect another) |
| Monohybrid vs. dihybrid inheritance (# of genes, # of chromosomes, # of alleles, ratios in the F2 generation) | Mono: 1 gene, 2 chromosomes, 2 alleles, 3:1 ratio Di: 2 genes, 4 chromosomes, 4 alleles, 9:3:3:1 ratio |
| Frequency of recombination meaning | the measure of distance between genes. If genes are closer together, crossing over is LESS likely, and if they are farther apart it is MORE likely. |
| Recombination formula | recombinant #/total # of organisms x 100 = _% |
| Linkage meaning | the tendancy of genes to be inherited together becuase they are on the same chromosome (a lack of independent assortment) |
| Multiplication vs. addition rule | addition is for exclusive events (OR events) and multiplication is for non exclusive (AND events) |