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Meiosis

biol 1210

QuestionAnswer
gametes reproductive cells that have half the # of chromosomes as a somatic cell (sperm & egg in animals & plants)
fertilization define the fusion of gametes (full chromosome # is restored)
meiosis define nuclear division that leads to halving of chromosome #
before meiosis each chromosome in 2n parent cell is replicated (during S phase of interphase) - when replication finishes, each chromosome has 2 identical sister chromatids that remain attached along their entire length by cohesins
meiosis stages meiosis I: 2 homologs of each chromosome pair separate into 2 daughter cells, each w 1 set of chromosomes & meiosis II: sister chromatids of each chromosome separate into 2 daughter cells (overall produces 4 haploid cells)
synapsis the pairing process of homologs during prophase I
bivalent the structure that results from synapsis btwn 2 homologs
non-sister chromatids the chromatids of the homologs during synapsis
1st & 2nd stages of synapsis & crossing over 1. as chromosomes condense, sister chromatids r joined along entire length by cohesins 2. homologs pair by synapsis & are held together by synaptonemal complex
3rd & 4th stages of synapsis & crossing over 3. breaks are made in DNA & cross over occurs btwn corresponding segments of non-sister chromatids 4. synaptonemal complex disassembles & homologs held together only at chiasmata (partial separation)
chiasma mark the sites of crossing over; where non-sister chromatids are attached during prophase I
prophase I events early - chromosomes condense, spindle apparatus forms, nuclear envelope breaks down, synapsis of homologs. Late - chiasmata visible (often multiple btwn sister chromatids), partial separation
metaphase I events movement of bivalents to metaphase plate
anaphase I events homologs separate & move to poles of cell
telophase I homologs finish moving to opposite poles, spindle apparatus disassembles
meiosis II no DNA synthesis occurs between the 2 meiotic divisions (no interphase). Meiosis II resembles mitosis w the split of sister chromatids during anaphase
what splits in anaphase I? What splits in anaphae II? I: homologs, II: sister chromatids
if a cell starts w 20 chromosomes, how many at end of meiosis I? At end of meiosis II? What is different? I: 10 each (n), II: 10 each. Chromosomes at end of meiosis I are replicated (2 chromatids); at the end of meiosis II they are unreplicated (1 chromatid)
describe animal life cycle 2n adult -> products of meiosis are (n) gametes with half chromosome # -> fertilization combines sperm (n) & egg (n) to make (2n) zygote, restoring original chromosome # -> mitosis & development grows baby
asexual reproduction v. sexual reproduction asexual: produces clones that are identical to one another & parent cell, sexual: produces offspring w unique chromosome complements (shuffles alleles of the parents into the offspring)
results of meiosis 4 cells with chromosome composition different from each other & from parent cells - independent shuffling of maternal & paternal chromosomes, crossing over during meiosis I, fertilization - haploid sets combine to create unique offspring
independent assortment homologs orient randomly in metaphase I. Each pair of chromosomes sorts maternal & paternal homologs into daughter cells independently of other pairs
# of combinations possible during independent assortment 2^n where n is haploid #. Ex. humans n = 23, 2^23 = 8.4 million possible combinations of chromosomes
crossing over produces recombinant chromosomes which combine genes from each parent - homologous portions of 2 non-sister chromatids swap places & combine DNA from 2 parents into 1 chromosome
random fertilization any sperm can fuse w any ovum (unfertilized egg). Ex. fusion of 2 gametes w 8.4 million possible chromosome combinations produces zygote w ~70 trillion diploid combinations
what leads to genetic variation during sexual reproduction? independent assortment, crossing over & random fertilization
random fertilization happens during meiosis I. T/F F. Random fertilization is NOT part of meiosis
what is the basis for matching homologs matched? Size (length), centromere position, and banding pattern (chromosomes are stained w dyes that show unique patterns of light & dark bands). Homologs r identical in all of these aspects
how do sister chromatids stay together in meiosis I and split in meiosis II? they r joined together along their entire length by cohesins which are protected by other proteins during meiosis I but during meiosis II the protection is removed and the cohesins are disassembled
Created by: AntBanana
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