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Molecular Technology
Karyotypes, Genetic Engineering, and Evidence
| Question | Answer |
|---|---|
| What does a karyotype show you? | A picture of your chromosomes, 23 pairs, 46 total chromosomes. |
| What are the first 22 chromosomes called? | Autosomes |
| What are the sex chromosomes for a female? | XX |
| What are the sex chromosomes for a male? | XY |
| Where do you look for sex chromosomes on a karyotype? | 23rd pair |
| Define nondisjunction | When a chromosome fails to separate during anaphase. |
| What are the two types of nondisjunction? | Trisomy and monosomy |
| What does a karyotype look like for Down's syndrome? | Extra chromosome, Trisomy 21. |
| What does a karyotype look like for Klinefelter's syndrome? | An extra X in a male; XXY. |
| What does a karyotype look like for Turner's syndrome? | X only, 45 chromosomes, Monosomy |
| What does a karyotype look like for Jacob's syndrome? | Extra Y, XYY. |
| Define genetic engineering. | DNA manipulation that alters an organism's DNA. |
| What are possible problems with genetic engineering? | Health risks and environmental risks. |
| How are we able to manipulate DNA in different species? | By using CRISPR-Cas9 gene editing. |
| How similar is human DNA? | Humans share 99.9% of DNA with each other. |
| Name two ways genetic engineering can be applied. | GMOs and medicine. |
| What is Polymerase Chain Reaction (PCR)? | A technique that makes copies of a specific DNA segment. |
| What is gel electrophoresis? | A method that separates DNA fragments by size using electricity. |
| What are three examples of how gel electrophoresis is used? | 1. Crime investigations, 2. Paternity tests, 3. Identifying genetic diseases. |
| What is gene therapy? | Treating disease by changing DNA to replace or fix genes. |
| What is CRISPR? | A gene editing tool that cuts DNA precisely |
| Explain cloning. | Making a genetically identical copy of an organism. |
| What is needed for cloning? | A somatic body cell and an egg cell (nucleus). |
| What are restriction enzymes? | They cut DNA at specific sequences. |
| What is evolution? | Change in characteristics of a species over many generations. |
| What do fossil records show? | Fossils found in different layers of rocks formed at different times. |
| What does biogeography suggest? | Organisms in similar environments look alike, indicating common ancestry. |
| What does embryology suggest about evolution? | Early stages of embryos of animals are very similar. |
| What do molecular homologies indicate? | Similarities and differences in DNA sequences show common ancestry. |
| What do anatomical homologies suggest? | Different functions but similar bone structures indicate common ancestry. |
| What do all five pieces of evidence suggest? | We came from a common ancestor. |
| What is a vestigial structure? | A structure that no longer has a function, e.g., appendix, wisdom teeth. |
| What are analogous structures? | Structures with the same function but different structures and no common ancestry. |
| What is gradualism in evolution? | Slow, steady change in species. |
| What is punctuated equilibrium in evolution? | Long periods of little change followed by rapid change. |