Question 1

What administration considerations apply to sulfasalazine?

Accepted Answer

Monitor stool for intact pills.
Make sure clients do not crush or chew the delayed-release tablets.
Mesalamine available orally, as a retention enema, and in suppository form.
Expect an orange-yellow discoloration of alkaline urine and skin (sulfasalaz

Question 2

What administration considerations apply to alosetron?

Accepted Answer

Make sure clients meet specific criteria and sign the required treatment agreement before administration.
Risk management program
Client, provider, pharmacist
Outlines potential adverse effects
Outlines criteria that must be met for treatment
Only fo

Question 3

What administration considerations apply to aluminum hydroxide?

Accepted Answer

Administer orally up to four times a day.
Make sure clients chew tablets thoroughly and follow with at least 8 oz of water
Do not give within 1 to 2 hr of administering drugs that interact with antacids.

Question 4

What administration considerations apply to dimenhydrinate?

Accepted Answer

Give dimenhydrinate orally, IM, or IV.
Give the initial dose 30 to 60 min before the activity that triggers nausea.
Give subsequent doses before meals and at bedtime.
Make sure clients do not swallow chewable tablets whole

Question 5

What administration considerations apply to psyllium?

Accepted Answer

Give orally one to three times a day with at least 8 oz of fluid.
Mix powdered forms with 8 oz of fluid.
Expect soft, formed stools 1 to 3 days after initiating therapy.
Tell clients that taking it before meals might reduce appetite.

Question 6

What administration considerations apply to ranitidine hydrochloride?

Accepted Answer

Give orally, IM, or IV.
Give with or without food (given with meals, immediately afterwards, or at bedtime does prolong effect).
Administer IV preparation slowly to avoid bradycardia.
Do not give antacids within 1 hr of administration.
Make sure cli

Question 7

What administration considerations apply to azathioprine?

Accepted Answer

Give orally or IV.
Give oral forms with food to minimize gastrointestinal upset.
Expect the onset of therapeutic effects to take up to 6 months.

Question 8

What administration considerations apply to lubiprostone?

Accepted Answer

Give orally twice a day with food or water to minimize nausea.
Make sure clients swallow the capsule whole.
Do not administer if client is experiencing diarrhea

Question 9

What administration considerations apply to sucralfate?

Accepted Answer

Administer orally on an empty stomach.
Give four times a day, 1 hr before the usual three mealtimes and again at bedtime.
Do not give antacids within 30 min of administration.
Do not give within 2 hr of administering fluoroquinolone antibiotics, warf

Question 10

What administration considerations apply to diphenoxylate/atropine and loperamide?

Accepted Answer

Diphenoxylate/atropine
Give orally.
Give 20 mg/day in 5-mg doses.
Continue for 24 to 36 hr to determine its efficacy.
Be aware that excessive doses of diphenoxylate can cause CNS effects similar to morphine, but atropine in high doses causes unpleas

Question 11

What administration considerations apply to metoclopramide?

Accepted Answer

Give orally, IM, or IV.
When treating chemotherapy-induced nausea and vomiting, give the drug IV slowly (over 15 to 30 min), starting 30 min before chemotherapy administration.
Administer 1 to 2 mg/kg initially with additional doses given every 2 to 4 h

Question 12

What administration considerations apply to misoprostol?

Accepted Answer

Administer orally four times a day, with meals and again at bedtime.
Confirm nonpregnant state before initiating drug therapy, as this drug can cause spontaneous abortion.
Make sure women of childbearing age use effective contraception during drug thera

Question 13

What administration considerations apply to omeprazole?

Accepted Answer

Administer orally once daily before the first meal of the day.
Make sure clients do not crush, chew, or break delayed-release capsules of omeprazole.

Question 14

What administration considerations apply to ondansetron?

Accepted Answer

Give orally or IV.
When treating chemotherapy-induced nausea and vomiting, give the drug IV slowly (over 15 min) starting 30 min before chemotherapy administration, and then 4 and 8 hr later.
When treating anesthesia-induced nausea and vomiting, give th

Question 15

What administration considerations apply to bisacodyl?

Accepted Answer

Give orally or by rectal suppository.
Expect semi-fluid stools within 6 to 12 hr with oral dosing and in 15 to 60 min with suppositories.
Tell clients to take the oral form at least 1 hr after drinking milk or taking antacids and not to crush or chew

Question 16

What administration considerations apply to docusate sodium and docusate sodium and senna?

Accepted Answer

Give orally with at least 8 oz of fluid.
Expect soft stools several days after initiating therapy.

Question	Answer
What administration considerations apply to sulfasalazine?	Monitor stool for intact pills. Make sure clients do not crush or chew the delayed-release tablets. Mesalamine available orally, as a retention enema, and in suppository form. Expect an orange-yellow discoloration of alkaline urine and skin (sulfasalaz
What administration considerations apply to alosetron?	Make sure clients meet specific criteria and sign the required treatment agreement before administration. Risk management program Client, provider, pharmacist Outlines potential adverse effects Outlines criteria that must be met for treatment Only fo
What administration considerations apply to aluminum hydroxide?	Administer orally up to four times a day. Make sure clients chew tablets thoroughly and follow with at least 8 oz of water Do not give within 1 to 2 hr of administering drugs that interact with antacids.
What administration considerations apply to dimenhydrinate?	Give dimenhydrinate orally, IM, or IV. Give the initial dose 30 to 60 min before the activity that triggers nausea. Give subsequent doses before meals and at bedtime. Make sure clients do not swallow chewable tablets whole
What administration considerations apply to psyllium?	Give orally one to three times a day with at least 8 oz of fluid. Mix powdered forms with 8 oz of fluid. Expect soft, formed stools 1 to 3 days after initiating therapy. Tell clients that taking it before meals might reduce appetite.
What administration considerations apply to ranitidine hydrochloride?	Give orally, IM, or IV. Give with or without food (given with meals, immediately afterwards, or at bedtime does prolong effect). Administer IV preparation slowly to avoid bradycardia. Do not give antacids within 1 hr of administration. Make sure cli
What administration considerations apply to azathioprine?	Give orally or IV. Give oral forms with food to minimize gastrointestinal upset. Expect the onset of therapeutic effects to take up to 6 months.
What administration considerations apply to lubiprostone?	Give orally twice a day with food or water to minimize nausea. Make sure clients swallow the capsule whole. Do not administer if client is experiencing diarrhea
What administration considerations apply to sucralfate?	Administer orally on an empty stomach. Give four times a day, 1 hr before the usual three mealtimes and again at bedtime. Do not give antacids within 30 min of administration. Do not give within 2 hr of administering fluoroquinolone antibiotics, warf
What administration considerations apply to diphenoxylate/atropine and loperamide?	Diphenoxylate/atropine Give orally. Give 20 mg/day in 5-mg doses. Continue for 24 to 36 hr to determine its efficacy. Be aware that excessive doses of diphenoxylate can cause CNS effects similar to morphine, but atropine in high doses causes unpleas
What administration considerations apply to metoclopramide?	Give orally, IM, or IV. When treating chemotherapy-induced nausea and vomiting, give the drug IV slowly (over 15 to 30 min), starting 30 min before chemotherapy administration. Administer 1 to 2 mg/kg initially with additional doses given every 2 to 4 h
What administration considerations apply to misoprostol?	Administer orally four times a day, with meals and again at bedtime. Confirm nonpregnant state before initiating drug therapy, as this drug can cause spontaneous abortion. Make sure women of childbearing age use effective contraception during drug thera
What administration considerations apply to omeprazole?	Administer orally once daily before the first meal of the day. Make sure clients do not crush, chew, or break delayed-release capsules of omeprazole.
What administration considerations apply to ondansetron?	Give orally or IV. When treating chemotherapy-induced nausea and vomiting, give the drug IV slowly (over 15 min) starting 30 min before chemotherapy administration, and then 4 and 8 hr later. When treating anesthesia-induced nausea and vomiting, give th
What administration considerations apply to bisacodyl?	Give orally or by rectal suppository. Expect semi-fluid stools within 6 to 12 hr with oral dosing and in 15 to 60 min with suppositories. Tell clients to take the oral form at least 1 hr after drinking milk or taking antacids and not to crush or chew
What administration considerations apply to docusate sodium and docusate sodium and senna?	Give orally with at least 8 oz of fluid. Expect soft stools several days after initiating therapy.

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GI drugs