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endocrine drugs
| Question | Answer |
|---|---|
| What administration considerations apply to glipizide? | Give orally 30 min before selected meal. Make sure clients swallow the sustained-release form whole and do not crush or chew it. |
| What administration considerations apply to repaglinide? | Give orally 30 min or less before meals, usually three times a day. Tell clients to skip a dose if they skip a meal and to add a dose if they add a meal. Do not exceed 4 doses a day |
| What administration considerations apply to metformin? | Give orally twice a day with the morning and evening meals (immediate-release) or once a day with the evening meal (extended-release). Make sure clients swallow the extended-release form whole and do not crush or chew it. |
| What administration considerations apply to pioglitazone | Give orally once per day with or without food. |
| What administration considerations apply to acarbose? | Give with the first bite of food, three times a day. Tell clients who skip a meal to also skip the dose usually taken with that meal and to take only one dose at the next meal. |
| What administration considerations apply to sitagliptin? | Administer orally alone or in combination with metformin (Janumet). Give with or without food. Give a reduced dosage to clients with severe renal impairment and low creatinine clearance. |
| What administration considerations apply to insulin - lispro, regular, NPH , insulin glargine? | Injection considerations Give subcutaneously (using an insulin syringe) or IV (Humulin R). Select an appropriate needle length for injecting insulin into subcutaneous tissue versus intradermal (too short) or intramuscular (too long). For insulin susp |
| What administration considerations apply to pramlintide? | Do not mix with insulin in the same syringe. Give subcutaneously thigh or abdomen prior to meals that contain at least 30 g of carbohydrates Rotate injection sites. Expect the peak action 20 min after dosing. Refrigerate unopened vials until their e |
| What administration considerations apply to exenatide? | Injection considerations Give subcutaneously into the thigh, abdomen, or upper arm up to 60 min prior to the morning and evening meals, not after meals. Rotate injection sites. Expect the peak action 2 hr after dosing. Preparation and care of the inje |
| What administration considerations apply to glucagon? | Give IV, IM, or subcutaneously. Expect unconscious clients to regain consciousness about 20 min after IV administration. Provide food after clients regain consciousness and can swallow. Be aware that, for severe hypoglycemia, IV glucose is the treatmen |
| What administration considerations apply to levothyroxine? | Give orally to treat hypothyroidism and IV to treat myxedema coma. Give daily on an empty stomach (at least 30–60 min before breakfast with full glass of water.). Measure baseline vital signs, weight, and height, and monitor periodically thereafter. |
| What administration considerations apply to propylthiouracil? | Give orally at regular intervals, such as every 8 hr. Measure baseline vital signs and weight and monitor periodically thereafter. Monitor T3 and T4 levels. |
| What administration considerations apply to iodine-131? | Give orally. Obtain a negative pregnancy test before administration. Measure baseline vital signs and weight and monitor periodically thereafter. Dosage is miniscule for thyroid disorders, larger for thyroid cancers Initiate radiation precautions for |
| What administration considerations apply to somatropin? | Give IM or subcutaneously (preferable). Dosage is based on weight. Given daily or several times a week Very costly Pediatric Clients: Obtain baseline height, weight, thyroid function, and growth hormone levels and monitor monthly; yearly X-rays of l |
| What administration considerations apply to desmopressin, vasopressin? | Administer orally, intranasally, subcutaneously, sublingually, or IV. Spray the nasal form high into the nasal cavity but not into the throat. Monitor blood pressure, intake and output, urine and plasma osmolality, and creatinine clearance. With IV vas |
| What administration considerations apply to hydrocortisone? | Give orally (with meals) for chronic adrenal insufficiency, as a total daily dose in the morning right after waking up or in divided doses (two thirds in the morning and one third in the early afternoon). Give IV for acute and emergency situations. Ob |
| What administration considerations apply to fludrocortisone? | Give orally daily or three times a week. Obtain CBC and electrolyte levels at baseline and periodically thereafter. Make sure clients wear a medical alert band. Expect lifelong therapy. |