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Toxicology Midwester
Question | Answer |
---|---|
Hydrocarbons - Petroleum distillates --> Symptoms | Pulmonary irritation, CNS Depression, severe pneumonitis after inhalation |
Hydrocarbons, petroleum distillates --> Treatment | Symptoms and support vital signs, emesis and gastric lavage are contraindicated unless patient is intubated |
Aromatic hydrocarbons --> Symptoms | Low dose --> CNS stimulation High Dose --> initial stimulation followed by depression. Kidney and liver damage (high dose or prolonged exposure), arrhythmias, aplastic anemia, leukemia. |
Aromatic hydrocarbons treatment | DO not induce emesis, gastric lavage if aspiration can be prevented. Diazepam to control convulsions |
Oxalic acid and oxalates Symptoms | local irritation and corrosion of the G.I. tract muscle weakness, convulsions and collapse due to calcium chelation renal tubular damage due to calcium oxalate precipitation |
Oxalic acid and oxalate treatment | Calcium in any form to precipiate oxalate, monitor renal functions and force fluids, calcium gluconate IV, DO NOT use gastric lavage or emetic compounds |
Mineral acids symptoms | irritation, inflammation and/or necrosis in all parts of the GI tract exposed to the corrosive substance death is usually due to unresolved hypovolemic shock after massive hemorrhage |
Mineral acids treatments | do not use gastric lavage or emesis after ingestion of acids dilute the acid with water give analgesics to reduce pain a non-specific antidote is milk of magnesia treat symptomatically and support vital signs |
Strong alkali symptoms | irritation, inflammation and tissue damage these agents are more penetrating than strong acids death is usually due to hypovolemic shock |