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Biology, Genetics
| Question | Answer |
|---|---|
| Mutation | A change in DNA that can result in a positive, negative or neutral effect. |
| Types of mutations | Deletion, Insertion, Substatution |
| Where do MUTATIONS happen | DNA |
| Why is it possible to have a neutral mutation | Some mutations like a substitution mutation can change the base pairs but it could still code for the same amino acid and therefore have no effect |
| Epigenetics | How environmental influences can affect gene expression |
| List some things that can change change your epigenome | Things that your parents, grandparents or anybody around you. How they acted, things that you did like smoking for example. |
| DNA methelation | When DNA is wrapped around histones. This causes it to be harder to read that DNA so it is not transcribed a lot or none at all, it depends how tightly it is wrapped around. |
| Promoter | Essential start signal and assembly point for transcription |
| Enhancer | Regulates the rate and frequency of transcription think of volume control |
| Enzyme | A protein that catalyzes (speeds up) a chemical reaction |
| What enzyme cuts | Restriction enzyme |
| What happens when a protein gets denatured | This means that it doesn't have the right shape and in protein world shape=function. If a protein is denatured it can't preform its function. |
| When can mutations happen | Error in transcription Exposure to chemicals Exposure to radiation |
| Natural selection | Breeding organisms of the same sepsis to get desired traits and characteristics. More Broad |
| Genetic Engeneering | Inserting the genes of interest into a plasmid to get the desired result or protein. More direct. |
| How does genetic engineering work | The first step is to take a bacterial plasmid and use a restriction enzyme to have it cut in the certain places. Then you take a piece of human DNA for the gene of interest and insert it into the plasmid and then use ligase to glue it back together. |
| Pros of genetic engeneering | More targeted results, there would be more starvation and nutrient deficiency, and it makes the lives of people with disorders better. |
| Cons of genetic engineering | We don't know all the side effects, reduced biodiversity, and GMO's can crossbreed with wild organisms. |