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DNA & RNA
| Term | Definition |
|---|---|
| Nucleic acids definition | Macromolecules found in all cells |
| Two main types of nucleic acids | DNA RNA |
| DNA | Deoxyribonucleic acid |
| RNA | Ribonucleic acid |
| Nucleic acids functions | Make protein Control cell activities Store & transmit genetic material |
| What DNA & RNA are composed of | Nucleotides |
| What are nucleotides? | Small building blocks |
| Three parts of a nucleotide | 1. 5 carbon sugar (deoxyribose or ribose) 2. Nitrogenous base 3. A phosphate |
| What sugar DNA nucleotides contain | Deoxyribose sugar |
| The four nitrogenous bases | Adenine Thymine Guanine Cytosine |
| How nucleotides bond | Complementary base pairing |
| Base that Adenine bonds with | Thymine |
| How many hydrogen bonds connect Adenine and Thymine? | 2 hydrogen bonds |
| Base that cytosine bonds with | Guanine |
| How many hydrogen bonds connect Cytosine and Guanine? | 3 hydrogen bonds |
| Poly nucleotide chain | Long chain if nucleotides |
| Purine bases | Adenine and Guanine |
| Pyramidine bases | Cytosine and Thymine |
| Appearance of DNA | Two polynucleotide chains joined together by hydrogen bonds according to the base pair rule |
| Double helix shape | Two polynucleotide chains twisted around each other |
| Nobel winning Scientists that proposed the double helix model | Watson and Crick |
| Location of nuclear DNA in a cell | Nucleus of the cell |
| Location of non nuclear DNA in a cell | Mitochondria Chloroplasts |
| Function of DNA | Stores the genetic code needed to make proteins in a cell |
| Gene definition | Section of DNA that codes for a specific protein |
| Non-coding DNA | Other sections of DNA that do not code for a protein Aka junk DNA |
| What chromosomes are made up of | DNA and protein |
| Amount of chromosomes humans have | 46 |
| Karyotype definition | Number and appearance of chromosomes in a somatic cell |
| Locus | The position or location of a gene on a chromosome |
| Codons | Three bases that form a code for one amino acid |
| How does the genetic code work in a gene? | The sequence of bases determines the sequence of amino acids in the polynucleotide chains joined together of protein. |
| 4 steps of DNA profiling | 1. Isolate the DNA 2. Cut the DNA 3. Separate the DNA fragments 4. Analyse the pattern of bands |
| Uses of DNA profiling | Solving crimes Paternity suits |
| Another member of the Nucleic acids | RNA |
| sugar RNA contains | Ribose sugar |
| Number of strands in RNA | Single stranded |
| Base that replaces Thymine in RNA | Uracil |
| Base Uracil binds to | Adenine |
| The type of base uracil is | Pyrimadine |
| Three types of RNA | 1. mRNA 2. tRNA 3. rRNA |
| mRNA | Messenger RNA |
| tRNA | Transfer RNA |
| rRNA | Ribosomal RNA |
| Function of RNA | Protein synthesis |
| Function of mRNA | Copies the DNA base code (transcription) Carries the genetic code out of the Nucleus to a ribosome |
| Function of tRNA | Transports an amino acid to a ribosome |
| Location of tRNA molecules in a cell | Cytoplasm |
| Function of rRNA | Helps mRNA attach to a ribosome |
| What ribosomes are made of | rRNA |
| DNA replication | The process of making a copy of DNA |
| Importance of DNA replication | Sexual reproduction Growth of an organism |
| When DNA replication occurs in the life cycle of a cell | Interphase |
| Steps in DNA replication - step 1 | Double helix unwinds Helicase breaks the hydrogen bonds and separates the DNA strands |
| Catabolic Enzyme in DNA replication | Helicase |
| Steps in DNA replication- step 2 | Free DNA nucleotides enter the nucleus from the cytoplasm The nucleotides align themselves to each template strand according to the rules of base pairing. DNA polymerase links the nucleotides together, forming two new strands |
| Anabolic enzyme in DNA replication | DNA polymerase |
| Steps of DNA replication- step 3 | Each new strand of DNA coils around a template strand, forming two double helixes |