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Campbell Chapter 9

Campbell Biology Chapter 9 12th edition

TermDefinition
Cellular Respiration The process by which cells break down glucose and other organic molecules to produce ATP, releasing CO₂, H₂O, and heat.
Purpose of Cellular Respiration To convert the chemical energy stored in food into usable energy (ATP) for cellular work.
Photosynthesis vs. Cellular Respiration Photosynthesis stores energy in glucose; cellular respiration releases that energy to form ATP.
Catabolic Pathways Metabolic pathways that break down complex molecules into simpler ones, releasing energy.
Anabolic Pathways Metabolic pathways that build complex molecules from simpler ones, requiring energy.
Oxidation The loss of electrons from a substance.
Reduction The gain of electrons by a substance.
Redox Reaction A reaction involving both oxidation and reduction; electrons are transferred between reactants.
Reducing Agent The substance that donates electrons in a redox reaction (becomes oxidized).
Oxidizing Agent The substance that accepts electrons in a redox reaction (becomes reduced).
Aerobic Respiration Respiration that requires oxygen; produces the most ATP.
Anaerobic Respiration Respiration that occurs without oxygen; uses another molecule as the final electron acceptor.
Fermentation A partial degradation of sugars that occurs without oxygen, regenerating NAD⁺ for glycolysis.
Equation for Cellular Respiration C₆H₁₂O₆ + 6 O₂ → 6 CO₂ + 6 H₂O + Energy (ATP + heat)
Glycolysis The first stage of cellular respiration; breaks down glucose (6C) into two pyruvate (3C) molecules. Occurs in cytosol.
Energy Investment Phase The first phase of glycolysis; cell uses 2 ATP to phosphorylate glucose.
Energy Payoff Phase The second phase of glycolysis; 4 ATP produced via substrate-level phosphorylation, 2 NADH formed.
Net Products of Glycolysis 2 Pyruvate, 2 ATP (net), 2 NADH, 2 H₂O.
Does Glycolysis Require Oxygen? No — it occurs whether or not oxygen is present.
Pyruvate Oxidation Conversion of pyruvate into acetyl CoA in the mitochondrial matrix. Produces 1 NADH and 1 CO₂ per pyruvate.
Coenzyme A (CoA) A sulfur-containing compound that helps form acetyl CoA from pyruvate.
Citric Acid Cycle (Krebs Cycle) Completes oxidation of glucose by breaking down acetyl CoA into CO₂ and transferring electrons to NADH and FADH₂.
Products (Per Turn) 3 NADH, 1 FADH₂, 1 ATP (via substrate-level phosphorylation), 2 CO₂.
Products (Per Glucose) 6 NADH, 2 FADH₂, 2 ATP, 4 CO₂ (since glucose forms 2 acetyl CoA).
Location of Citric Acid Cycle Mitochondrial matrix (cytosol in prokaryotes).
Oxidative Phosphorylation Production of ATP using energy derived from redox reactions in the electron transport chain.
Electron Transport Chain (ETC) A series of proteins in the inner mitochondrial membrane that pass electrons and pump H⁺ ions to create a gradient.
Final Electron Acceptor Oxygen (O₂); combines with electrons and H⁺ to form water.
Chemiosmosis The use of the H⁺ gradient (proton-motive force) to drive ATP synthesis through ATP synthase.
ATP Synthase The enzyme that synthesizes ATP from ADP + Pᵢ using the proton-motive force.
Proton-Motive Force The gradient of H⁺ across the mitochondrial membrane that powers ATP production.
ATP Yield from Oxidative Phosphorylation About 26–28 ATP per glucose.
Purpose of Fermentation To regenerate NAD⁺ from NADH so glycolysis can continue without oxygen.
Alcohol Fermentation Pyruvate converted to ethanol and CO₂ (e.g., yeast).
Lactic Acid Fermentation Pyruvate reduced to lactate (e.g., muscle cells under low oxygen).
ATP Yield from Fermentation 2 ATP per glucose (from glycolysis only).
Facultative Anaerobes Organisms that can survive using either fermentation or cellular respiration (e.g., yeast, muscle cells).
Catabolic Versatility Carbohydrates, fats, and proteins can all feed into cellular respiration pathways.
β-oxidation Process that breaks down fatty acids into acetyl CoA units for the citric acid cycle.
Amino Acid Deamination Removal of the amino group before amino acids enter the citric acid cycle.
Anabolic Pathways and Biosynthesis Intermediates from glycolysis and the citric acid cycle can be used to build macromolecules.
Purpose of Acetyl CoA formation Links glycolysis to the citric acid cycle. Pyruvate → acetyl CoA + CO₂ + NADH.
Why two turns per glucose Each glucose produces 2 pyruvates → 2 acetyl CoA → 2 cycles.
Role of NADH/FADH₂ Temporary electron carriers; store high-energy electrons for the ETC.
Why O₂ is essential (for aerobic) It pulls electrons through the ETC, maintaining flow; without it, the chain backs up.
Fermentation vs. Anaerobic respiration Fermentation: no ETC, no oxygen; Anaerobic: ETC with different final electron acceptor.
Energy yield comparison Aerobic: ~30–32 ATP; Anaerobic: less (~2–28 ATP depending on organism); Fermentation: 2 ATP.
Electron Transport Chain A series of protein complexes in the inner mitochondrial membrane that pass electrons and use the released energy to pump H⁺ ions, creating a gradient.
Chemiosmosis The movement of H⁺ ions down their concentration gradient through ATP synthase, producing ATP.
Anaerobic A process that occurs without oxygen.
Beta Oxidation The process of breaking down fatty acids into acetyl-CoA for use in cellular respiration.
Created by: trumoo312
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