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BIOL 1141 Exam 1

terminology, concepts for Exam 1

QuestionAnswer
cells basic units of structure and function in a living organism
number of cells in the human body approximately 75 trillion
intracellular fluid fluid inside a cell
extracellular fluid or intercellular fluid fluid outside of a cell
vascular fluid extracellular fluids that circulate
plasma fluid part of the blood, contained in blood vessels
lymph fluid contained in lymphatic vessels
interstitial fluid fluid in between cells, in the tissues. Not found in blood or lymphatic vessels
light microscope uses light as the illuminating source
electron microscope uses electrons as the illuminating source, provides greater magnification and detail compared to light microscope.
3 general regions of a cell plasma membrane, cytoplasm, nucleus
plasma membrane thin and flexible outer boundary of the cell, defines the cell, contains contents
selectively permeable characteristic of a cell membrane that controls what can enter and leave
2 types of membrane transport passive and active
passive processes do not require energy (ATP)
diffusion passive process. Movement of substance from area of high concentration to an area of low concentration.
concentration gradient difference in concentration between two areas that allows movement of materials between the two areas
simple diffusion small molecules can move directly through the lipid part of the cell membrane (ex - O2, CO2, urea)
facilitated diffusion proteins form channels in the cell membrane through which molecules can pass
osmosis movement of water from areas of low solute concentration to areas of high solute concentration
active process requires ATP or other energy source, molecules move against the concentration gradient
specific transport mechanisms proteins transport substances across the membrane
bulk transport mechanisms use vesicles to move things into or out of the cell
vesicle fluid filled pocket of the lipid bilayer
endocytosis formation of a vesicle from the membrane of a cell
3 different types of endocytosis phagocytosis, pinocytosis, receptor-mediated endocytosis
phagocytosis brings in fairly large molecule into a cell - "eats" the substance and then brings it into the cell
pinocytosis when a cell "drinks" in extracellular fluid
receptor-mediated endocytosis cell wants a specific thing, so a protein is used to "attract" the specific substance
exocytosis secretion or release of waste or other molecules through formation of a vesicle that attaches to the membrane to release contents. The vesicle then becomes part of the cell membrane.
three types of intercellular junctions tight junction, desmosome, gap junction
tight junction prevents leakage between cells
desmosome strengthens the cell-to-cell contacts
gap junctions facilitates communication between cells
cytoskeleton internal skeleton made from proteins, gives cells their shape
microfilaments little rods, fine filaments of contractile protein, involved in muscle contraction and other types of intracellular movement, part of cytoskeleton
microtubules little tubes, support the cell and give it shape, part of the cytoskeleton
intermediate filament protein fibers, composition varies. part of the cytoskeleton, resist tension forces acting on a cell
cilia short, hairlike extensions that are on the free surface of the cell. made from microtubles. help move things along an epithelial surface
flagella singular cell extension that gives a cell motility
microvilli folds of the plasma membrane that increase the surface area of the cell to allow for quick exchange of material or absorption of material
nucleus control center of the cell, contains most of the cell's DNA
nuclear envelope membrane that surrounds the nucleus of a cell
nucleolus dense, spherical bodies within the nucleus
chromatin DNA molecules plus their "protein wrap"
chromosome "colored body" - contains a single, long strand of DNA
number of chromosomes in humans 46 (23 pairs)
cell cycle cell division -> cell division G1 (growth), S (DNA synthesis), G2 (growth), M (mitosis)
stages of mitosis prophase, metaphase, anaphase, telophase
examples of cells that cycle regularly skin, hair, most epithelia
examples of cells that do not cycle regularly skeletal muscle, brain cells (nerves), cardiac muscle
human life cycle egg/sperm -> zygote -> adult -> egg/sperm
zygote fertilized egg
meiosis type of division in which egg and sperm cells are produced, produces cells with half of the required number of chromosomes
differentiation process by which genetically identical cells specialize in structure and function
2 roles of cells 1)general function, 2) specialized function
terminal (w/ differentiation) describes a cell that no longer divides, usually happens once a cell specializes
stem cells less than fully differentiated cells
stem cells in adults limited differentiation, usually only produce a limited number of cells
stem cells in embryos can give rise to many different cell types
cancer collection of diseases in which cells do not behave appropriately, often form a solid mass called a tumor
tumor solid mass of cells
hyperplagia increased cell division, increase in cell numbers
anaplasia inappropriate/incomplete differentiation in cells
benign usually not life-threatening unless impacts vital organs; do not usually spread
malignant often life-threatening, can grow, spread and disrupt normal physiology
metastisis spread of cancer cells to other body systems, new tumors
causes of cancer free radicals (molecules that disrupt DNA), carcinogens, radiation, mutant genes
treatments chemotherapy, surgery, radiation
types of cancers carcinoma, sarcoma, lymphoma, leukemia
carcinoma cancer of epithelial tissues, about 90% of all cancers, usually solid tumors
sarcoma cancer of connective or muscle tissue, usually form solid tumors
lymphoma cancer of lymphocytes (white blood cells)
leukemia cancer of blood cells
organelles little organs within a cell
interphase stages G1, S and G2 of the cell cycle (everything except mitosis)
cytokinesis separation of the cell into two separate cells at teh end of the cell cycle, "cells moving apart"
neoplasm abnormal mass of proliferating cells
gamete mature reproductive cell that can fuse with another mature reproductive cell
histology study of biological tissues
tissue group of cells with similar function and structure
extracellular matrix material outside and in between cells, made and secreted by the cells
four types of tissues epithelial, connective, muscle, nerve
function of epithelial tissues cover and line surfaces and hollow organs (serosa); form membranes, glands that secrete; filtration, absorption, protection, secretion, sensory reception, excretion, diffusion
characteristics of epithelial tissue -no blood vessels (in connective tissue underneath) -heal relatively quickly -tend to replace themselves quickly -contain stem cells -tightly packed -small amount of extracellular matrix -cells have direction
free (apical) surface cell membrane in contact with the lumen, surface (superficial) layer of stratified epithelia
attached (basal) surface surface of the cell that touches the basement membrane, bottom layer in stratified epithelia
basement membrane membrane between epithelial cells and underlying connective tissues
different types of epithelia 1 simple squamous epithelium 2 simple cuboidal epithelium 3 simple columnar epithelium 4 stratified squamous epithelium 5 stratified cuboidal epithelium 6 stratified columnar epithelium 7 pseudostratified columnar epithelium 8 transitional epitheli
endocrine glands secrete into plasma, hormones
exocrine glands secrete into the lumen of ducts which lead to a surface (ex, sweat, salivary glands, mammary glands)
unicellular gland a singular cell that secretes (ex, goblet cell)
multicellular gland multiple cells that secrete into a duct (ex, salivary, mammary)
types of connective tissues 1 loose (areolar) connective tissue 2 dense connective tissue (reg & irreg) 3 adipose tissue 4 reticular connective tissue 5 elastic connective tissue 6 hyaline cartilage 7 elastic cartilage 8 fibrocartilage 9 bone 10 blood
types of muscle tissue 1 skeletal muscle 2 smooth muscle 3 cardiac muscle
functions of connective tissues support, provide blood supply to epithelial tissues at the surface, fill spaces, attach organs, surround organs, transport (blood), storage of energy (adipose)
characteristics of connective tissues cells are more widely dispersed, blood vessels throughout (except cartilage), extracellular matrix is an important part of the tissue
cell types found in connective tissues 1 fibrocyte (fibers) 2 adipocyte (fat) 3 osteocyte (bone) 4 chondrocyte (cartilage)
ground substance extracellular matrix, mixture of proteins, carbohydrates and water, can be fluid (blood), gel-like (cartilage) or solid (bone)
collagenous fibers thick fibers, strong, resist stretching
elastic fibers thin, allow tissues to stretch and recoil
reticular fibers delicate, provide support for fragile organs
white blood cell types macrophage (clean up), neutrophils (immune defense), mast cells (inflammation)
examples/functions of loose (areolar) connective tissue papillary layer of the dermis, often found under epithelia; fills in spaces, has ample blood supply
specific functions of adipose tissue storage of energy, protection, insulation
examples/functions of dense connective tissue tendons, ligaments (dense regular) reticular layer of the dermis (dense irregular)
examples/functions of elastic connective tissues?? lots of elastic fibers, aorta
examples/functions of cartilage no blood vessels, contain lacunae, does not heal well ends of bones at joints (hyaline) ear (elastic) knees, pelvis, vertebrae (fibrocartilage - provides support)
components of blood erythrocytes (red blood cells) - carry O2 leukocytes (white blood cells) - immune protection thrombocytes (platelets) - clotting
functions of muscle tissue movement; move materials throughout the body (ex, cardiac muscle), move parts of the body (ex, skeletal muscle), locomotion, generate heat to help maintain constant body temperature
characteristics of muscle tissue can shorten - contractile tissues; elongated, excitable, elastic
functions/characteristics of skeletal muscle tissue voluntary muscle; fibers, striations, multiple nuclei per fiber, cannot divide,
functions/characteristics of smooth muscle tissue involuntary muscle; no striations, one nucleus per cell, can form sheets/layers of cells
functions/characteristics of cardiac muscle tissue involuntary muscle; striations, intercalated discs, individual cells "locked" from end to end to form one long arrangement
functions/characteristics of nerve tissue located within the nervous system (brain, spinal cord, nerves); communication and coordination of body systems, electrical tissue, lots of fibers, 2 types of cells - neurons and neuroglia (supporting cells)
body membranes organs; thin, flexible sheet-like structures made up of 2 or more tissues
functions of body membranes cover the body, line body cavities, cover organs, line lumen of hollow organs, separate/compartmentalize the body, secrete lubricants, protect/support/anchor organs
types of body membranes epithelial (serous, mucus, cutaneous) connective tissue (fascial - superficial and deep, skeletal)
epthelial membranes epithelia with underlying connective tissue includes serous membranes, mucus membranes and cutaneous membranes
serous membranes located on body cavity walls or on organs; simple squamous epithelium + connective tissue; secrete serous fluid; facilitate movement of an organ within a body cavity, protection
mesothelium pleural membrane
mucus membranes located at the openings of cavities (ex, nose, mouth, airways, stomach); different types of epithelial tissues, often with goblet cells or with separate glands that open up onto epithelium); secrete mucus; protection, lubrication, defense from pathogens
cutaneous membranes skin (integument), located at the surface of the body; stratified squamous epithelium + loose connective + dense irregular tissue; protection
integument skin
connective tissue membranes contain 2 or more connective tissues, stronger than epithelial membranes
superficial fascia hypodermis, subcutaneous layer; located at the bottom layer of the skin, superficial to skeletal muscle; adipose tissue + areolar connective + dense connective tissue
deep fascia deep to hypodermis, extends to and into skeletal muscle; mostly dense connective tissue with some areolar and adipose
skeletal membranes periosteum, perichondrium, synovial membranes; mostly dense connective tissue with some aerolar
periosteum membrane around bones, contains cells that produce more bones
perichondrium membrane around cartilage, supplies blood vessels
synovial membrane joints, produces fluid that lubricates joints
organ system 2 or more organs that work together to perform a specific function for the body
parts of the integumentary system skin, accessory organs (hair follicles, hair, nails, sebaceous glands, sudoriferous glands, ceruminous glands, mammary glands
thickness for different types of skin very thick 6 mm (ex, sole of foot) very thin .5 mm (ex, eyelids) average thickness 1.5 mm
functions of the integumentary system protection, regulation of body temperature, prevention of water loss, sensory receptors, synthesis of some chemicals (Vit D), excretion of some waste (sweat), communication and recognition, displays symptoms, allows entry of fat soluble materials
5 layers of epidermis stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, stratum basale
stratum basale contains stem cells, contains keratinocytes and melanocytes
stratum corneum dead, keratinized squamous cells
keratinocytes squamous cells that accumulate the protein keratin
keratin non-water-soluble protein that is fibrous, strong and resists water
melanocytes responsible for pigmentation of the skin and hair, stimulated by UV rays, contain stem cells; aging and pregnancy can effect melanocytes; located in stratum basale
melanin primary pigment, dark brown, protective, absorb UV light
melanoma cancer of the skin; forms in the melanocytes, often metastisizes
albinos little or no pigment
dermis thick layer that binds epidermis to underlying tissue
epidermis outermost layer of skin
2 layers of the dermis papillary layer (areolar connective tissue) reticular layer (dense irregular connective tissue)
dermal papillae fingerlike projections of the papillary layer
accessory organs contained in the dermis blood vessels, muscle fibers, sensory receptors, hair follicles, exocrine glands
hypodermis below the dermis, not actually a part of the skin, superficial fascia; anchors the skin to underlying surfaces (mostly muscles)
hair follicles produce hairs
nails heavily keratinized epithelial cells; protection, manipulation
exocrine glands secrete into ducts, then onto epidermal surface; epithelial tissues
sebaceous glands sebum = oil; lubricate the skin, condition surface; active at puberty; often open into hair follicles
suderiferous glands sweat glands
eccrine sweat glands evaporative cooling; forehead, hands, feet, back; triggered by need to cool, stress; secrete mainly water
apocrine sweat glands secrete scented molecules via sweat; active at puberty; associated with hair follicles, hair acts as a wick; armpits, groin; responsible for body odors
ceruminous glands secrete cerumen = wax; in ear canal; modified sweat glands; earwax lubricates and protects the tympanic membrane
mammary glands produce milk in recently delivered females; both men and women have mammary glands
Created by: pinklrt98
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