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AP Bio Unit 2

AP Biology

TermDefinition
Cell Membrane Fluidity The flexibility of the plasma membrane is influenced by temperature, fatty acid saturation, and cholesterol.
Unsaturated Fatty Acids In phospholipids, these have double bonds that increase membrane fluidity.
Saturated Fatty Acids In phospholipids, these lack double bonds and make membranes more rigid.
Amphipathic Molecule A molecule with both hydrophilic and hydrophobic regions, like a phospholipid.
Lipid Rafts Specialized membrane microdomains rich in cholesterol that organize cell signaling molecules.
Transport Proteins Membrane proteins that help move substances across the membrane.
Channel Proteins Provide hydrophilic passageways for specific molecules or ions.
Carrier Proteins Bind specific molecules, undergo shape change, and transport them across the membrane.
Ion Channels Protein channels allowing specific ions to pass; can be gated by voltage or ligands.
Membrane Potential The voltage across a cell’s plasma membrane created by ion distribution.
Electrochemical Gradient Combined force of electrical and concentration gradients driving ion movement.
Proton Pump Active transport mechanism that moves protons across membranes to create potential energy.
ATP Synthase Enzyme that synthesizes ATP using a proton gradient across a membrane.
Endomembrane System System of membranes including ER, Golgi, lysosomes, and vesicles for transport and processing.
Vesicle Small membrane sac that transports materials between organelles or to the plasma membrane.
Secretory Pathway Pathway for proteins destined for secretion or membranes (Rough ER → Golgi → vesicle → membrane).
Glycoprotein Protein with carbohydrate chains attached; important for cell recognition.
Glycolipid Lipid with a carbohydrate chain that aids in cell identification.
Cell Recognition The ability of a cell to distinguish one type of cell from another, often via surface molecules.
Signal Transduction Pathway Process by which a cell converts an external signal into a specific response.
Ligand A molecule that binds to a receptor and triggers a cellular response.
Receptor Protein Protein that receives and binds signaling molecules, initiating a signal transduction cascade.
G Protein-Coupled Receptor (GPCR) Membrane receptor that activates a G protein when bound by a ligand.
G Protein A molecular switch that relays signals from GPCRs to other signaling proteins.
Second Messenger Small molecule (like cAMP or Ca²⁺) that relays and amplifies intracellular signals.
cAMP (Cyclic AMP) A common second messenger involved in many signal transduction pathways.
Protein Kinase Enzyme that transfers phosphate groups to proteins, activating or deactivating them.
Protein Phosphatase Enzyme that removes phosphate groups from proteins, turning off signaling pathways.
Signal Amplification Each step in a signal transduction cascade activates multiple downstream molecules.
Phosphorylation Cascade Series of protein activations through phosphorylation events in cell signaling.
Cell Communication The process of cells detecting and responding to signals in their environment.
Local Signaling Communication between nearby cells through direct contact or short-distance signaling.
Paracrine Signaling Type of local signaling where cells release molecules that act on nearby cells.
Synaptic Signaling Nerve cell releases neurotransmitters that cross synapse to target cell.
Endocrine Signaling Long-distance signaling where hormones travel through the bloodstream to target cells.
Hormone Chemical messenger secreted into body fluids that affects target cells at distant sites.
Reception First step of cell signaling where the signal molecule binds to a receptor.
Transduction Series of molecular events that convert the signal into a cellular response.
Response Final stage of cell signaling where the cell changes behavior or gene expression.
Feedback Mechanisms Biological processes that regulate systems by increasing or decreasing activity.
Negative Feedback Process that reduces the output of a system, maintaining homeostasis.
Positive Feedback Process that amplifies a response, driving it to completion (e.g., childbirth contractions).
Apoptosis Programmed cell death that removes damaged or unnecessary cells.
Autophagy Process in which lysosomes digest damaged organelles or cell components.
Cell Junctions Structures that connect cells and facilitate communication or adhesion.
Desmosome Proteins Cadherins that anchor cells together in tissues under mechanical stress.
Gap Junction Proteins Connexins that form pores connecting animal cells’ cytoplasms.
Plasmodesmata Proteins Callose-lined channels allowing small molecules to pass between plant cells.
Surface Receptor Receptor located in the plasma membrane that binds polar signaling molecules.
Intracellular Receptor Receptor inside the cell that binds nonpolar, lipid-soluble molecules like steroid hormones.
Steroid Hormones Lipid-based hormones that pass through membranes and bind to intracellular receptors.
Gene Expression Response Type of cell response that changes transcription or translation of specific genes.
Homeostasis Stable internal condition maintained through feedback and cell signaling.
Osmoregulation Process by which cells or organisms maintain water balance.
Turgor Pressure The pressure exerted by water inside the plant cell against its wall.
Plasmolysis When a plant cell loses water in a hypertonic solution, causing the membrane to pull away from the wall.
Cotransport Example The uptake of sucrose into plant cells powered by proton gradients established by proton pumps.
Membrane Potential Example Resting potential in neurons where the inside is negatively charged relative to outside.
Endocytosis Example White blood cell engulfing bacteria.
Exocytosis Example Neurons releasing neurotransmitters into a synapse.
Mitochondria Function Convert energy from organic molecules into ATP through cellular respiration.
Chloroplast Function Convert solar energy into chemical energy through photosynthesis.
Lysosome Function Break down waste and damaged organelles using hydrolytic enzymes.
Golgi Function Modify, sort, and package proteins for secretion or delivery to organelles.
Smooth ER Function Synthesize lipids, metabolize carbohydrates, and detoxify drugs.
Rough ER Function Produce and fold proteins for secretion or for use in membranes.
Peroxisome Function Oxidize fatty acids and detoxify harmful compounds.
Cytoskeleton Function Provide structural support, movement, and intracellular transport.
Microtubule Motor Proteins Dynein and kinesin proteins that move vesicles along microtubules.
Dynamic Equilibrium State in which molecules continue to move but overall concentration remains constant.
Water Potential The potential energy of water in a system; drives osmosis (Ψ = Ψs + Ψp).
Solute Potential Component of water potential determined by solute concentration (always negative).
Pressure Potential Component of water potential caused by physical pressure on a solution.
Cell Theory The cell is the basic unit of life; all living things are made of cells, and all cells come from pre-existing cells.
Prokaryotic Cell A cell lacking a nucleus and membrane-bound organelles; includes bacteria and archaea.
Eukaryotic Cell A cell containing a true nucleus and membrane-bound organelles; includes plants, animals, fungi, and protists.
Plasma Membrane A selectively permeable phospholipid bilayer that regulates the entry and exit of substances.
Phospholipid Bilayer The main structural component of membranes; hydrophilic heads and hydrophobic tails create a semi-permeable barrier.
Selective Permeability Property of biological membranes allowing some substances to pass while restricting others.
Cytoplasm The region between the nucleus and plasma membrane containing organelles and cytosol.
Nucleus Membrane-bound organelle that contains the cell’s DNA and controls gene expression.
Nuclear Envelope Double membrane surrounding the nucleus, containing pores for RNA and protein exchange.
Nucleolus Region inside the nucleus responsible for ribosome synthesis.
Ribosome Structure made of rRNA and proteins; the site of protein synthesis.
Free Ribosomes Ribosomes floating in cytosol; produce proteins for use within the cell.
Bound Ribosomes Ribosomes attached to rough ER; produce proteins for export or for membranes.
Endoplasmic Reticulum (ER) Network of membranes involved in protein and lipid synthesis.
Rough ER ER studded with ribosomes; synthesizes and modifies proteins.
Smooth ER ER without ribosomes; synthesizes lipids, detoxifies toxins, and stores calcium ions.
Golgi Apparatus Stack of flattened membranes that modifies, sorts, and packages proteins for secretion or delivery.
Lysosome Membrane-bound sac of digestive enzymes that breaks down macromolecules and old organelles.
Peroxisome Organelle that breaks down fatty acids and detoxifies harmful substances, producing hydrogen peroxide.
Vacuole Storage organelle; large central vacuole in plants stores water and maintains turgor pressure.
Mitochondrion Organelle that generates ATP through cellular respiration; has its own DNA and double membrane.
Chloroplast Plant organelle where photosynthesis occurs; contains chlorophyll and its own DNA.
Endosymbiotic Theory Idea that mitochondria and chloroplasts originated from prokaryotic cells engulfed by ancestors of eukaryotes.
Cytoskeleton Network of fibers that maintains cell shape, secures organelles, and enables cell movement.
Microtubules Hollow protein tubes made of tubulin; form spindle fibers and cilia/flagella.
Microfilaments Fine protein threads made of actin; involved in cell movement and muscle contraction.
Intermediate Filaments Rope-like filaments that provide structural support and anchor organelles.
Centrosome Region near the nucleus that organizes microtubules; contains centrioles in animal cells.
Centriole Cylindrical structure in animal cells that helps organize cell division.
Cilia Short, hair-like projections used for movement or moving fluids over a cell surface.
Flagella Long, whip-like tail used for locomotion in some cells.
Cell Wall Rigid structure outside the plasma membrane in plants, fungi, and bacteria providing support and protection.
Extracellular Matrix (ECM) Collection of proteins and carbohydrates outside animal cells providing structural and biochemical support.
Plasmodesmata Channels between plant cell walls that allow for communication and transport.
Tight Junctions Connections between animal cells forming a watertight seal.
Desmosomes Anchoring junctions that hold animal cells together through intermediate filaments.
Gap Junctions Channels between adjacent animal cells allowing ions and small molecules to pass.
Passive Transport Movement of molecules across the membrane without energy input.
Diffusion Movement of molecules from high to low concentration until equilibrium is reached.
Facilitated Diffusion Passive transport aided by membrane proteins.
Osmosis Diffusion of water through a selectively permeable membrane.
Tonicity The ability of a surrounding solution to cause a cell to gain or lose water.
Isotonic Solution Solution with equal solute concentration inside and outside the cell; no net water movement.
Hypotonic Solution Solution with lower solute concentration outside the cell; water enters, cell swells.
Hypertonic Solution Solution with higher solute concentration outside the cell; water leaves, cell shrinks.
Active Transport Movement of molecules against the concentration gradient requiring energy (ATP).
Sodium-Potassium Pump Transport protein that pumps Na+ out and K+ into the cell, maintaining membrane potential.
Endocytosis Process by which cells take in materials via vesicles formed from the plasma membrane.
Exocytosis Process of vesicles fusing with the plasma membrane to release contents outside the cell.
Phagocytosis “Cell eating”; a type of endocytosis where large particles are engulfed.
Pinocytosis “Cell drinking”; a type of endocytosis that brings in fluids and dissolved substances.
Receptor-Mediated Endocytosis Selective uptake of molecules based on receptor-ligand interactions.
Surface Area-to-Volume Ratio Ratio affecting cell efficiency; smaller cells have higher ratios for better material exchange.
Compartmentalization Organization of cellular functions into membrane-bound organelles for efficiency.
Fluid Mosaic Model Model describing the plasma membrane as a fluid combination of lipids and proteins.
Cholesterol Inserts into the phospholipid bilayer to regulate membrane fluidity.
Integral Protein Protein embedded within the lipid bilayer, often spanning the membrane.
Peripheral Protein Protein attached to the surface of the membrane, not embedded.
Aquaporin Protein channel that facilitates water diffusion across membranes.
ATP (Adenosine Triphosphate) Main energy currency of the cell produced by mitochondria.
Cell Fractionation Laboratory technique to separate organelles for study based on size and density.
Proton Gradient Difference in proton concentration across a membrane driving ATP synthesis.
Cotransport Active transport of one substance indirectly driving the transport of another.
Signal Transduction Pathway by which a signal is converted into a cellular response.
Created by: Leo12345
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