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TL Cirrhosis Drugs
Drug therapy for Cirhosis
| Question | Answer |
|---|---|
| What drug is used for heamostasis and control of bleeding in esophageal varices and to constrict the splanchnic arterial bed? | Vasopressin ( Pitressin) |
| What drug is used to reduce portal venous pressure and slow bleeding of varices? | Propranolol (Inderal) |
| What drug acidifies the bowel, traps ammonia and causes it to be excreted from the body? | Lactulos (Cephulac) |
| What drug causes a decrease in bacterial flora so that there is less bacterial break down of protein in the bowel and thus less ammonia produced? | Neomycin sulfate |
| Why do we give magnesium sulfate to a patient with liver dysfunction? | Hypomagnesemia occurs with liver dysfunction |
| What supplement do we give to improve clotting abnormalities? | Vitamin K |
| What drugs do we give to decrease stomach acidity? | H2 blockers like ranitidine (Zantac) or cimetidine (Tagamet) or Proton pump inhibitors like Pantoprazole ( Protonix) |
| What drug do we give to block the action of aldosterone and spare potassium? | Aldactone (Spironolactone) |
| What drugs do we give to inhibit reabsorption of sodium and secretion of potassium? | amiloride (Midamor) and Triamterene (Dryenium) |
| What drug do we give because it acts on the proximal kidney tubules to decrease reabsorption of sodium and water? | Chlorothiazide (Diuril) or Hydrochlorothiazide (Hydrodiuril) |
| What drug do we give because it acts on the distal kidney tubules and loop of Henle to prevent reabsorption of sodium and water? | Furosemide (Lasix) |
| What drugs can be given to help relieve pruritis related to bile salt deposits in the skin? | Cholestyramine (Questran), or hydroxazine (Atarax) |