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Lab Exam #2 Guide

Anatomy & Physiology I Lab

TermDefinition
Histology The study of tissues
Tissue (origin of word) From “tissu” = woven; groups of similar cells performing a common function
4 Tissue Groups Epithelial, Connective, Muscle, Nervous
Function of nervous tissue Internal communication; regulates & controls body functions
Nervous tissue locations Brain, spinal cord, nerves
Function of muscle tissue Contracts to cause movement; pumps blood, flushes urine, moves body
Types of muscle tissue Skeletal (bones), Cardiac (heart), Smooth (walls of hollow organs)
Functions of epithelial tissue Forms boundaries, protects, secretes, absorbs, filters, synthesizes hormones
Locations of epithelial tissue Skin (epidermis), GI tract lining, hollow organs
Types of epithelium Covering & lining epithelium; Glandular epithelium (endocrine/exocrine; uni/multicellular)
5 characteristics of epithelial tissue Polarity, Supported by connective tissue, Specialized contacts, Avascularity, Regeneration
Apical surface specializations Smooth, Microvilli, Cilia
Endothelium Slick lining of cardiovascular & lymphatic system; facilitates diffusion
Mesothelium Lines ventral cavities & organs (serous membranes)
Basement membrane Basal lamina + reticular lamina; connects epithelium to connective tissue
Tight junctions & desmosomes Specialized contacts forming continuous sheets of cells
Connective Major functions Binding & support, protection, insulation, transportation (blood
Connective Common characteristics Mesenchyme origin, varying vascularity, extracellular matrix (non-living)
Matrix components Ground substance + fibers; cells embedded in matrix
Ground substance Interstitial fluid + proteins
Fibers Collagen, elastic, reticular
Resident cells Immature (-blasts) & mature (-cytes) forms
Fibroblasts Produce fibers
Chondroblasts Produce cartilage
Osteoblasts Produce bone
Hematopoietic stem cells Produce all blood cells
Adipocytes Produce fat
White blood cells Immune defense & tissue repair
Mast cells Inflammatory response
Macrophages Phagocytic cells
Muscle tissue function Highly specialized to contract; produces movement
Muscle cells shape Elongated; long axis for contraction
Muscle types recap Skeletal, Cardiac, Smooth; voluntary & involuntary
Neurons Specialized to receive stimuli & conduct impulses; long processes up to 3 feet
Neuroglia Supporting cells; protect, support, insulate neurons
Neuron structure Cell body & cytoplasm extend into long cell processes; allows long-distance impulse conduction
Skin surface area 1.2–2.2 m²
Skin body weight 7%
Skin Thickness 1.5–4 mm thick
Skin layers Epidermis (epithelial) & Dermis (dense connective tissue)
Accessory organs Glands, hair, nails, sensory receptors
Hypodermis Subcutaneous tissue; adipose & areolar; not part of skin
Protection functions Insulates, cushions, prevents water loss, chemical/bacterial defense, thermal protection
Regulatory & metabolic functions Regulates heat, cutaneous sense organs, blood reservoir, mini-excretory, Vitamin D synthesis
Keratinocytes Most abundant; produce keratin for durability/protection
Merkel cells Light touch receptors
Free nerve endings Pain receptors
Langerhans (dendritic) cells Immunity; phagocytosis
Melanocytes Produce melanin; protect nucleus from UV
Papillary layer Superficial; areolar CT; fingerprints; Meissner’s corpuscles; capillaries
Reticular layer Deep; dense irregular CT; arteries, veins, glands, Pacinian corpuscles
Thick Skin all 5 layers, palms/soles/fingertips
Thin Skin no stratum lucidum, hair present
Dermal papillae Superficial; form friction ridges; enhance grip; sweat pores; fingerprints
Cleavage (tension) lines Parallel collagen fibers; incisions heal better
Flexure lines Dermal folds near joints; visible on hands, wrists, fingers, soles, toes
Krause corpuscles Cold; reticular dermis
Golgi-Mazzoni corpuscles Deep pressure & compression; reticular dermis
Pacinian corpuscles Deep touch & vibration; lower reticular dermis
Ruffini corpuscles Skin stretch & light touch; upper reticular dermis
Meissner corpuscles Light touch & vibration; upper papillary dermis
Merkel cells Light touch; lower epidermis
Stratum Corneum Most Superficial layer, 20-30 layers of dead cells, flat membranous sacs filled with keratin
Root hair plexus Light touch & hair movement; reticular dermis
Nail body Visible attached portion
Free edge Portion growing away from body
Root Embedded in skin; adheres to nail bed
Nail folds Skin folds overlapping nail borders
Eponychium Thick proximal nail fold; cuticle
Nail bed Stratum basale beneath nail
Nail matrix Thick proximal nail bed; nail growth; keratinized, nonliving material
Lunula White crescent at proximal nail matrix
Hair structure Medulla (center), cortex, cuticle
Root Portion within follicle
Shaft Projects from scalp
Hair bulb Germinal epithelial cells at follicle base; dead material in shaft
Follicle Formed from epidermal & dermal cells
Papilla Dermal tissue protruding into hair bulb; provides nutrition
Arrector pili muscle Smooth muscle; hair “stands up”
Sebaceous (oil) glands All over except palms/soles; sebum lubricates; active in puberty; acne = infection
Eccrine sweat glands Clear; water, salts, urea; heat regulation
Apocrine sweat glands Axillary/genital; milky protein/fat-rich; nutrient for microorganisms; pheromone-like
Basal cell carcinoma Most common; arises from stratum basale
Squamous cell carcinoma Arises from stratum spinosum; can metastasize
Melanoma Arises from melanocytes; highly malignant
1st degree Burn Epidermis; red, painful, mild swelling; heals days
2nd degree Burn Epidermis + part dermis; blistered, painful; heals weeks; may scar
3rd degree Burn Full thickness; white/brown/black; numb; grafts required
Created by: mdonovan8742
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