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macro-proteins
ap bio unit one powerpoint 3
| Term | Definition |
|---|---|
| protein | -molecule made up of polypeptides (polymer of amino acids) -shape determines function |
| amino acids | -carboxyl and amino group -20 different proteins with unique side chains -determines unique chemical and physical aspects -side chains interact to determine shape and function |
| amino acid side chain groups | 1. nonpolar (hydrophobic) 2. polar (hydrophilic) 3. ionic/charged (hydrophilic) |
| peptide bonds | -carboxyl group bonded next to amino group |
| polypeptides | -many amino acids linked by peptide bonds -each has unique amino acid and directionality -each end is unique (N-terminus and C-terminus) -sequence of AAs determines shape (function) -R group interacts and polypeptide twists -forms protein |
| N-terminus | -one end free amino group |
| C-terminus | -one end free carboxyl group |
| five functions of proteins | -1. antibody -2. messenger -3. structural -4. enzyme -5. transport/storage |
| antibody | -a protein function -protects body from disease |
| messenger | -a protein function -transmits signals (hormones) |
| structural | -a protein function -offers structure and support |
| enzyme | -a protein function -carry chemical reactions -creates new molecules |
| transport/storage | -a protein function -binds to and carries small atoms and molecules |
| four levels of protein structures | -primary, secondary, tertiary, quaternary -all levels determine function |
| primary level | -determined by genes -dictates secondary and tertiary levels |
| secondary level | -hydrogen bonds cause it to coil and fold in polypeptide backbone |
| tertiary level | -3D folding caused by side chain interactions -reinforced by hydrophobic and disulfide bridges |
| disulfide bridges | -covalent bonds between sulfur and two cysteine monomers |
| quaternary level | -association of 2+ polypeptides -only in some proteins |
| pleated sheet | -hydrogen bonds with polypeptides side by side |
| alpha helix | -hydrogen bonds every 4th amino acid |
| elements in protein | -Carbon -Hydrogen -Oxygen -Nitrogen -Sulfur |
| formation order | -amino acid to -peptide to -polypeptide to -protein |