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Antiprotozoal Drugs

Kaplan

QuestionAnswer
DOC for Leishmaniasis Stibogluconate
DOC for Trypanosomiasis Nifurtimox (Chagas’ disease) Arsenicals (African)
DOC for Giardisis Metronidazole
DOC for Trichomoniasis Metronidazole
DOC of Amebiasis Metronidazole
DOC of Toxoplasmosis Pyrimethamine + Sulfadiazine (TMP-SMX)
What are the Antimalarial drugs in Chloroquine sensitive regions? Chloroquine+ Primaquine (prophylaxis)
What are the Antimalarial drugs in Chloroquine resistant region? Atovaquone- proguanil
What are the side effects of Antimatter;aerial drugs? (2) 1.Hemolytic anemia in G6PD deficiency 2. Cinchonism (Quine) —> GI upset, ocular dysfunction + ringing of the ear
What are the classes of antibiotics that cause hemolytic anemia in G6PD deficiency? (2) 1. Sulfonamides 2. Quines
What are the drugs for Helmethic infections (Nematodes)? (2) 1. Albendazole, Mebendazole 2. Pyrantel pamoate
MOA of Albendazole DECREASE glucose uptake and DECREASE microtubular structure
MOA of Pyrantel pamoate? Nm agonist —> spasticity paralysis
DOC for treatment of custodies and trematodes? Praziquantel (increase Calcium influx, increase vacuolization)
Created by: DVD27
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