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Meningitis/ seizures
| Question | Answer |
|---|---|
| What is Meningitis? | Inflammation of the meninges (protective membranes around brain & spinal cord). Caused by bacteria (serious), viruses (more common, milder), or fungi (immunocompromised) |
| Key Risk Factors for Meningitis | Viral infections (mumps, measles), Bacterial infections (sinusitis, pneumonia), Fungal (Cryptococcus), Immunosuppression, Skull fractures, Crowded living. |
| How does Meningitis progress (Pathophysiology)? | Germs enter CNS → meningeal inflammation → increased CSF & sluggish flow → increased intracranial pressure (ICP). Can lead to brain herniation, hydrocephalus, sepsis |
| Classic Triad of Meningitis Symptoms | Fever, Nuchal rigidity (stiff neck), Altered mental status. |
| Fever, Nuchal rigidity (stiff neck), Altered mental status. | Severe headache, Photophobia, N/V, Confusion, Lethargy, Seizures, Red macular rash (meningococcal). Brudzinski’s sign: Flex neck → hips & knees bend. Kernig’s sign: Flex hip & extend knee → pain behind knee. |
| Most Important Diagnostic Test for Meningitis & What it shows | Bacterial: cloudy, ↓ glucose, ↑ WBC, ↑ protein. Viral: clear, normal glucose, ↑ WBC. |
| Nursing Priorities for Meningitis Patients | solate (droplet precautions for bacterial), Monitor neuro status, Reduce ICP (HOB 30°, avoid coughing/straining), Fever management, Pain relief, Minimize stimuli, Maintain fluid & electrolytes, Monitor for complications. |
| Key Medications for Meningitis | Ceftriaxone + Vancomycin (bacterial); Ciprofloxacin prophylaxis (close contacts). Anticonvulsants: Phenytoin (if seizures). Analgesics: Acetaminophen, ibuprofen. |
| Potential Complications of Meningitis | Increased ICP (risk of herniation), SIADH (fluid retention, hyponatremia), Septic emboli (gangrene, stroke). |
| How to Prevent Meningitis | Vaccines: Hib, Pneumococcal, Meningococcal (MCV4, especially for college students). |
| Define Seizure vs. Epilepsy | Sudden, excessive electrical discharge in brain → change in behavior/movement/consciousness. Epilepsy: Chronic disorder with ≥2 unprovoked seizures ≥24 hrs apart. |
| Types of Generalized Seizures | tonic-clonic: Stiffening (tonic), then jerking (clonic). LOC, incontinence, postictal confusion. Absence: Brief staring spells. Myoclonic: Sudden brief jerks. Atonic: Sudden loss of muscle tone → fall. |
| types of Focal (Partial) Seizures | Simple partial: No LOC. Local motor or sensory symptoms. Complex partial: Impaired awareness. Automatisms (lip-smacking). |
| Risk Factors for Seizures | Brain injury (trauma, stroke), Infection (meningitis), Metabolic (hypoglycemia), Alcohol/drug withdrawal, Genetic, Toxins. |
| Phases of a Seizure | Aura:Warning sign. Ictal: Active seizure. Postictal: Recovery (confusion, fatigue). |
| What is Status Epilepticus? | Seizure >5 min OR repeated seizures without recovery. Medical emergency, can lead to brain damage/death. |
| What is SUDEP? | Sudden Unexpected Death in Epilepsy. Usually occurs during sleep, linked to non-adherence to meds. |
| Nursing Actions DURING a Seizure (DOs and DONTS | DO: Stay with patient, Protect airway (side-lying), Loosen clothing, Note timing & characteristics, Suction & O2 ready, Reorient/assess injuries after. DON'T: Restrain or put anything in mouth. |
| Key Diagnostics for Seizures | EEG (electrical activity), MRI/CT (structural causes), Labs (glucose, electrolytes, tox screen). |
| Common Antiepileptic Drugs (AEDs) & Key Side Effects/Monitoring | Phenytoin (Dilantin): gingival hyperplasia, ataxia. Carbamazepine (Tegretol): Liver fx, visual changes. Valproate (Depakote): Liver toxicity, pancreatitis. Lamotrigine (Lamictal): Severe rash risk. Levetiracetam (Keppra): Fatigue, dizziness. |
| Important Patient Teaching for AEDs | Take same time daily, DO NOT stop abruptly, Watch interactions (OCPs, warfarin), Carry medical alert ID, Driving restrictions. |
| Other Treatments for Seizures/Epilepsy (Beyond Meds) | Vagal Nerve Stimulator (VNS), Deep Brain Stimulation, Surgery (remove seizure focus). |