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Histo Epithelia

Epithelial cell review

QuestionAnswer
Epithelia originate from which embryonic layers? All of them
T or F. Epithelia contain both blood vessels and nerve endings. F. They only contain nerve endings. The blood vessels remain proximal to epithelia in the BM.
Mesothelium Covers the mesentery and some organs
Endothelium Lines the circulatory system
Carcinomas vs. adenocarcinomas Carcinomas arise from epithelia, while adenocarcinomas arise from glandular epithelial cells.
Epithelial carcinomas can be detected by __________. Anti-IF abs
Stratified columnar epithelia typically presents with what two structures? Goblet cells and cilia
Basement membrane is composed of what Basal lamina and lamina reticularis
Basal lamina is composed of what Lamina rara/lucida (att. to epi cells) and a lamina densa
Basal lamina is composed of protein types? Type IV collagen, glycoproteins (laminin, fibronectin), and proteoglycans.
Hemidesmosomes (adhesive Junc.) Integrins/collagen XVII;Plectin or BPAG1;IF
Tight junctions (Zonula occludens) Occludin, claudin, JAM; ZO-1 proteins; actin
Desmosomes (Macula Adherens) Cadherins; desmoplakin; IF
Adherent junctions (Zonula Adherens) Cadherins; catenins; actin
Gap Junction Structure 6 transmembrane proteins named connexins form a cylinder called connexon. Connxons from adjacent cells form a channel together.
Gap Junction Pore size and size exclusion. 1.5nm sized pore and excludes proteins larger than 1000 Da.
Glycocalyx Fuzzy extracellular coat containing polysaccharides and hydrolytic enzymes. Functions in digestion and cell surface recognition.
Stereocilia Specialized cilia found in the epididymal cells (secretion+absorption). Also mechanorecptors in the ears.
Microvillia vs Cilia Length 1-2um vs 6-12um long.
Cilia are assembled from ________. Basal bodies (modified centrioles)
What are the 2 functions of cilia 1-Transport of extracellular material (mucous, sinus fluids, CSF). 2-Structural support in retinal photoreceptors;olfactory epithelia; and some chemo/osmotic-receptor cells.
Myoepithelial cells Contractile cells located between epithelia and basal membrane
Neuroepithelail cell are located in... Auditory hair cells; taste bud cells; photoreceptors of retina; olfactory epithelia; other chemo/osmotic-receptors
Created by: jgenere
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