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Systemic Lupes Er.
pn 141 test 1 book: med surg nursing pg 1065
| Question | Answer |
|---|---|
| def of SLE | a chronic inflammatory connective tissue disease. it effects multiple body systems. |
| how does it range in severirt (from what to what ) | mild and episodic to rapidly fatal |
| who is it most common in | women then men, in asians and hispanics and african americans |
| what is the cause | unknown |
| what do the autoantibodies that are produced target in the body | they target normal body cells, and cell components like DNA, blood cells, and proteins involved in coagulation |
| the autoantibodies correspond with their antigen to form immune complexes, where are these immune complexes deposited | in the connective tissue of blood vessels, lumphatic vessels, and other tissues |
| the deposit of immune responses into the connective tissue causes what | an inflammatory response that damages the tissues |
| what organ is frequently damaged | the kidneys |
| what are some common affected tissues | MS system, brain, heart, spleen lungs, GI tract, skin, and peritoneum |
| early in the disease, the s/s of SLE mimic what other disease; what are these s/s | RA; fever, anorexia, malaise, weight loss, and joint pain, inflammation, and stiffness |
| what is a common skin s/s; and where SLE name came from (LUPES) | butterfly rash; located across the cheecks and bridge of the nose (Lupes= bite of the wolf) |
| s/s: skin | butterfly rash on face, phtosensitivity, alopecia, ulcers (mouth, lips, nose) |
| s/s: respiratory | pleurisy, pleural effusion |
| s/s: GI | anorexia, N/V, abdominal pain, diarrea |
| s/s: MS | arthralgias, joint swelling and effusion, morning stiffness |
| s/s: neurologic | depression, dementia |
| s/s: sensory | conjunctivitis, photophobia |
| s/s: CV | pericarditis, vaculitis, venous or arterial thrombosis |
| s/s: hematologic | anemia, leukopenia, thrombocytopenia |
| s/s: reproductive | preg. induced HTN, edema and proteinuria, sponateous abortion or fetal death |
| similar to RA, SLE has periods of remission followed by _____________ | exacerbation |
| what happens to the exacerbations over time | the severity and number of them decrease |
| what so they have an increased risk for; this is also the leading cause of death in pt with SLE | infection |
| other causes of death | efefcts on kidneys and CNS involvment |
| s/s: unrinary | proteinuria, renal failure |
| what is the Dx based on | H & P, diagnostic tests |
| why is antinuclear antibodies study done | all clients with SLE have it, also many pt w/o SLE have it too |
| Why is anti-DNA antibody testing done | it is a more specific indicator of SLE |
| C-reactive protein levels: What are they like with SLE | they are elevated |
| erythrocyte sedimentation rate (ESR): what is that with SLE | it is elevated |
| what will the CBC show with SLE | anemia and low RBC, WBC and platelet count |
| why are renal funtion studies ordered | to assess for kidney damage |
| meds: what meds are used to manage joint pain and inflammation, fever and fatigue | aspirin and NSAIDS |
| meds: why is the antiplatelet action of aspirin particularily useful in pt with sLE | b/c it helps prevent thrombosis (a s/s of SLE) |
| meds- antimalarial drugs: hydrochloroquine (Plaquenil) - what can it damage | the retina ofthe eyes , an ophthalmologic exan is done q 6 months |
| meds: when are corticosteroids used | to treat severe life threatening s/s of SLE, or long-term to prevent organ damage |
| meds- corticosteriods: side effects | cushingiod effects, wt gain, HTN, infection, accelterated osteoporosis, hypokalemia. |
| because of photosensitivity, what should be avoided | sun exposure, use sun screen more than 30 SPF |
| why is oral contraception not recommended | it can trigger an acute episode of SLE |
| tx for kidney issues | maintain adequate fluid intake, keep DM under control, keep HTN low, decrease stresses, ace inhibitors |
| ppl with SLE are at risk for what | kidney failure, premature atherosclerosis |
| why do they need incerased amounts of sleep | because they don't have enough cortisol in the body |
| why should the sun be avoided | it can cause flare ups |
Created by:
jmkettel
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