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Cardio Final Exam Dr
| Generic | Brand | Class/MOA |
|---|---|---|
| warfarin | coumadin, jantoven | vitamin K antagonist |
| dabigatran | pradaxa | direct thrombin inhibitor |
| rivaroxaban | xarelto | factor xa inhibitor, preventing prothrombin from becoming thrombin to clot |
| apixaban | eliquis | factor xa inhibitor, preventing prothrombin from becoming thrombin to clot |
| enoxaparin | lovenox | LMWH |
| disopyramide, QUINIDINE, procainamide | class 1A (IM) Na channel blockers, slow depolarization of ventricle, slowing down the HR. disopyramide and procainamide -b lock Na and K channels QUINIDINE - Blocks NA, K, Alpha and Muscarinic receptors (evening out some of the alpha blocker effects) | |
| LIDOCAINE, mexiletine | xylocaine, mexitil | class 1 B (rapid) Na channel blockers LIDOCAINE - only blocks Na channels, widening QRS and slowing HR, increasing excitement threshold |
| flecainide, propafenone | tambocor, rithmol | class 1C (slow) Na channel blockers, pills in the pocket to use for Afib flecainide (tambocor) - blaock NA, K and some Ca propafenone (rithmol) - blocks Na and some Beta receptors, further lowering HR, increasing PR interval |
| metoprolol succinate | toprol XL | beta blocker, slow the heart rate by extending the PR interval |
| carvedilol IR | coreg | beta blocker, slow the heart rate by extending the PR interval |
| bisoprolol | zebeta | beta blocker, slow the heart rate by extending the PR interval |
| esmolol | brevibloc | beta blocker, slow the heart rate by extending the PR interval |
| atenolol | tenormin | beta blocker, slow the heart rate by extending the PR interval |
| amiodarone | pacerone, nexterone, cordarone | K channel antagonist, blocks Na, K and Ca channels, lengthening the PR, QRS and QT intervals, all of them. Intense drop in heart rate, go to to get arrhythmias to just stop |
| ibutilide | corvert | IV infusion, Ikr channel blocker, can cause excessive QT increase |
| dofetilide | tikosyn | Oral, Ikr channel blocker, can cause excessive QT increase |
| sotalol | betapace | Beta antagonist and K channel blocker lowering heart rate in two ways, longer QT and PR |
| diltiazem | cardizem | NDHP CCB slow the conduction through the Av node by CCBing, lengthening Pr and lowering HR |
| verapamil | calan, verelan | NDHP CCB slow the conduction through the Av node by CCBing, lengthening Pr and lowering HR |
| adenosine | adenocard | IV bolus, agonist to adenosine type 1 receptors |
| digoxin | digitek, lanoxin | Na/K pump antagonist, + inotropic agent, slows Av node conduction making the PR longer, HR lower |
| dronedarone | multaq | amiodarone analog, has less thyroid and pulmomary toixity than amiodarone. but has severy liver tox. |
| nicardipine IV | cardene | DHP CCB |
| clevidiine IV | cleviprex | DHP CCB |
| labetalol IV | trandate | Non selective BB and alpha blocker |