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unit 4 flashcards

unit 6 flashcards

QuestionAnswer
Direct communication examples immune cells, plasmodesmata, gap junctions
Local communication examples Neurotransmitters, plant immune, quorum sensing, morphogens in embryonic development
Long distance communication examples Insulin, Human growth hormone, Thyroid hormones, Testosterone, Estrogen
Step one of cell signaling reception; the reception of a signal (LIGAND) by a receptor protein on/within a cell membrane, or inside the cell. (SHAPE OF LIGAND MUST MATCH RECEPTOR SHAPE)
Step two of cell signaling transduction; passes on the signal received at the receptor. Usually multistep, allows for amplification of a signal.
Step three of cell signaling response; Nuclear (regulates protein synthesis, DNA into mRNA) or Cytoplasmic (Protein activity outside of nucleus)
Three major types of transmembrane receptors G-Protein-coupled receptors, receptor tyrosine kinases, ion channel receptors
Relay molecules Usually proteins, changes shape to continue signal
Secondary messangers Secondary to primary signal, not proteins, can move through cell membranes, cAMP and Ca2+
Common responses of cell signaling Mitosis, secretion of molecules (hormones), gene expression (making of protein)
Mutations in signal transduction pathways Changes shape of receptor proteins, usually will negatively affect the transduction of signals
Agonist ligand that binds to a receptor and causes a response.
Antagonist a ligand that binds to a receptor and inhibits a response.
Quorum sensing the regulation of gene expression in response to fluctuations in cell-population density.
Apoptosis Programmed cell death, usually caused by damaged/infected cells
ligand a molecule that binds to a receptor to send a signal that triggers a reaction
receptor protein a protein on or inside of a cell membrane, attaches to a ligand to send signal to the cell
protein kinases Enzymes that transfer phosphate groups from ATP to a protein
adenylyl cyclase Enzyme that converts ATP into cAMP
phosphorylation adding a phosphate group to a molecule
dephosphorylation removing a phosphate group form a molecule
transcription factor a protein that binds to DNA sequences to regulate transcription of genes
why do cells divide either reproduction (asexual organisms), or cell growth/repair (multicellular)
4 phases of the cell cycle g1 (g0), S, G2, M
mitosis/cytokinesis division of the cell
G1 phase Cell growth
S phase DNA replication
G2 phase More growth, spindles form to prepare for mitosis
G0 phase Cells are not divided (not continuing cycle to mitosis)
homeostasis maintaining a stable internal state despite external changes
Negative feedback systems a response that counteracts or reduces change (regulation of body temp., blood sugar control)
Positive feedback systems a response that amplifies or enhances change (childbirth, blood clotting)
Chromosomes highest condensed structure of DNA, contains genetic material
chromatin unraveled condensed structure of DNA
histones spherical proteins involved in chromatin structure
nucleosomes DNA + histones
somatic cells any body cell not involved in reproduction
gametes cells involved in reproduction
Cyclins binds to CDKs to activate them
Cyclin-dependent kinases activated if bound to a cyclin. if not bound, protein is inactive
2 results of a failure to regulate cell cycle 1. Cell death (premature apoptosis) 2. Cancer (uncontrolled vell division)
Single chromatid one chromatid, still considered ONE chromosome
Sister chromatids two chromatids, considered ONE chromosome
centrosome organizes the microtube spindle fibers, crucial for cell division
kinetacore attach site for the spindle microtubes (attaches onto centromere)
spindle fibers protein structures composed of microtubes to help separate chromosomes by pulling them apart during cell division
motor proteins proteins that use chemical energy from ATP to generate movement within cells
actin/myosin two proteins that are needed for muscle contraction
parent cell the cell that undergoes division
daughter cells the cells produced from the division of the parent cell
Mitosis stages (in order) Interphase, prophase, prometaphase, metaphase, anaphase, telophase
Created by: noah.j
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