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Moa meds
| Question | Answer |
|---|---|
| Inhibited by antifungal(fluconazole, terbinafine) | Ergosterol |
| Blocked by B-lactam antibiotics (penicillin, cephalosporin, vancomycin) | Peptidoglycan synthesis |
| Inhibited by aminoglycosides and tetracyclines | 30s ribosomal action |
| Inhibited by antibiotics (chloramphenicol, erythromycin, clyndamycin, Linezolid) | Action of 50s ribosomal |
| Drugs such as infliximab and Adalimumab | Monoclonal antibodies to tumor necrosis factor -alpha |
| Trimethoprim sulfamethoxazole | Inhibit folate dihydrofolate reductase synthesis |
| Prevents microtubule depolymerization | Paclitaxel use in ovarian ca, non small cell lung ca, metastatic breast ca |
| Arrest the cell cycle in S phase | 5-Fluorouracil use for slow growing tumors breast, ovarian, pancreatic, colorectal, gastric carcinoma. |
| Intercalates DNA during G2 | bleomycin use testicular tumor, lymphomas, squamous cell carcinoma |
| Acts at any stage in cell cycle is a DNA alkylator | Cyclophosphamide use leukemia, testicular and gynecological cancer |
| Prevents mitotic spindle causing cell cycle arrest | Vincristine |