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What is a mutation? changes in dna sequence
list 3 things that can cause mutation radiation, chemicals, mistakes in dna replication
Substitution : one base for another, not changing sequence.
Insertion : One base is added to the DNA sequence, changing the sequence by one.
Deletion : One base is deleted , changing sequence.
Why were all the words in the chromosomes only 3 letters long? Because DNA is counted in 3.
Which of the three mutations is the least harmful? Why? Substitution, because it swaps one for another, not changing the whole sequence.
Which of the following mutations could be passed to offspring? a) translocation in a cheek cell b) duplication in a female's egg c) frameshift mutation in male sperm d) inversion in a chromosome of a liver cell. THERE IS MORE THAN ONE! b and c
Why were b and c correct? because they produce offspring
WHAT ARE THE FOUR BASES FOUND IN DNA Thymine, Cytosine, Adenine, Guanine.
When are substitution mutations usually made? WHY? DNA replication, flexibility of molecule.
A silent mutation is a kind of mutation that changes a base within the sequence, but the result stays the same kind of amino acid. Why does it have no effect on the overall protein? Because it only changes one base pair.
What does insertion mutation do to the sequence? Inserts, moving bases up by one.
What does deletion mutation do to the sequence? Deletes, moves everything by one.
Chromosome mutation : involve changes in the number or structure of chromosomes
Gene mutation : a change in one or more genes.
DNA stores genetic instructions for making __ called ___ proteins, genes.
Ribose is the sugar found in __, while Deoxyribose is the sugar in __ RNA, DNA.
In eukaryotic cells, DNA is found in the __ nucleus
DNA has __ strand(s) of nucleotides whereas RNA has __ strand(s) of nucleotides. two, one.
DNA'S nucleotide strands are __ complementary
Rosalind Franklin's work with x-ray diffraction helped determine DNA's shape as being __ helical
The __ model of DNA was developed by James Watson and Francis Crick. double helix
DNA codes for the instructions for life in its sequence of __ nitrogen bases
to copy DNA, __ bonds are broken between ___. hydrogen, nitrogen base pairs.
when DNA is replicated, new nucleotides attach to the open ladder by using the __ rules. nitrogen base-pairing
According to Erwin Chargaff's rule, guanine bonds to __ and adenine bonds to __. cytosine, thymine.
What is the process of creating two identical molecules of DNA using original nucleotide strands as templates for the new nucleotide strands? DNA replication
What is the enzyme that unwinds and separates the two DNA strands of nucleotides? helicase
What is the enzyme that bonds new strands of nucleotides onto the open DNA ladder? polymerase
What is the stringy form of DNA and associated proteins called? Chromatin
What are proteins that help the DNA coil into chromosomes? Histone
In mitosis, which cell divided to produce more body cells? Parent cell
In mitosis, which cells are created or produced? Daughter cells
What are the two identical strands of DNA coiled up into chromosomes called? duplicated chromosome/ sister chromatids
DNA ladder reads, "TACCAGA," what will other side read? ATGGTCT
A duplicated chromosome has two identical ___ sister chromatids
T OR F, humans have 46 chromosomes in each body cell? Yes, humans typically have 46 chromosomes in each body cell, which is made up of 23 pairs of chromosomes; one set coming from the mother and the other from the father.
T or F, the two DNA molecules produced during DNA replication are identical Yes, the two DNA molecules produced during DNA replication are considered identical to each other and to the original DNA molecule.
T or F, DNA is replicated four times before cell division starts F. DNA is replicated only once before cell division starts
When a human body cell divides, the daughter cells will have 23 chromosomes each. Each daughter cell will have half of the original 46 chromosomes, or 23 chromosomes. Yes.
Cancer is uncontrolled cell division yes
A tumor is the death of new cells producing a mass of cells False, tumors are growth.
The cell cycle begins and ends at the start of __ interphase
A __ tumor has not spread, while a __ tumor has spread throughout the body. benign, malignant.
During cytokinesis in plants, a __ forms, completing cell division. cell plate
___ has three phases, G1, S, and G2. interphase
During ___ DNA replication occurs; forming sister chromatids. S phase.
Many cells of the body such as nerve cells do not repeatedly go through the cell cycle; rather these cells pause at ___, which is where normal growth and maturation occurs in cells. G1 phase
Order of mitosis phases? Prophase, Metaphase, Anaphase, Telophase, Cytokinesis
Fibers that connect chromosomes to the centrioles, aids in the division of sister chromatids spindle
location where the spindle attaches to the sister chromatid/duplicated chromosome centremeres
Sister chromatids come apart and move away to opposite sides of the cell. What phase is this? Anaphase
Chromatin coils into chromosomes and becomes visible, nuclear envelope dissolves. What phase is this? Prophase
Two new nuclei are visible as nuclear envelopes reform; chromosomes uncoil into chromatin. What phase is this? Telophase
Chromosomes are pulled and lined up in the middle of the cell by the spindle. What phase is this? Metaphase
____ is the final step of cell division, it physically separates the cell's cytoplasm into two new cells. In animals cells the two new cells pinch off from each other. Cytokinesis
Prophase This is the first phase of mitosis. The genetic material in the nucleus condenses and the duplicated chromosomes become visible. Spindle fibers connect to the chromosomes on either side.
Metaphase This is the second phase of mitosis. The centromeres of duplicated chromosomes line up in the middle of the cell. The spindle fibers and centrioles connect to the chromosomes on either side.
Anaphase This is the third phase. The chromosomes will be separated and move apart to opposite sides of the cell. The sister chromatids are considered separate chromosomes. The spindle fibers
Telophase Final stage of mitosis. The chromosomes turn back into a tangle of chromatin. The nuclear envelope of the nucleus redevelops. Cytokinesis occurs at the end of this phase to split the cytoplasm.
G0 phase Resting place in interphase where the cell is not dividing nor preparing to.
G1 phase the growth phase, where cells are provisioned with metabolites while most biosynthesis occurs.
S phase the stage of the cell cycle where DNA is copied, or synthesized.
G2 phase The second growth phase starts to prepare the cells with newly replicated DNA for entry into the mitosis phase by putting in place the necessary organelles for mitosis.
Centromere a constricted region of a chromosome
Centriole a minute cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division.
Created by: melulu
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