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HIV Drugs

Pharmacology drugs for HIV

TermDefinition
Enfuvirtide(Fuzeon) Class Fusion inhibitor
Enfuvirtide: Pharmacological action Blocks HIV from attaching to and entering CD4T cells limiting HIV spread.
Enfuvirtide: Therapeutic Use Treatment of HIV that is unresponsive to other antiretrovirals
Enfuvirtide: Contraindications/ Precautions Contraindications: Severe liver disease, Lactation, allergy to enfuvirtide, clients who have both HIV and hepatitis B infections Precautions: Mild liver disease, Kidney impairments, Bacterial pneumonia.
Enfuvirtide: Nursing Interventions Rotate injection sites, bring solution to room temp, monitor for bacterial pneumonia, monitor for systemic hypersensitivity reaction
Enfuvirtide: Administration Subcutaneous twice each day
Enfuvirtide: Client education Report tenderness, discoloration, swelling, or hardened area. Report cough, fever, or shortness of breath to provider
Maraviroc(Selzentry): Class CCR5 antagonists
Maraviroc: Pharmacological action Prevents HIV from entering lymphocytes by binding to CCR5 on cell membranes.
Maraviroc: Therapeutic Use Treats HIV infection in combination with other antiretroviral medications
Maraviroc: Complications Respiratory symptoms, CNS effects, Hepatoxicity, Pseudomembranous colitis
Maraviroc: Contraindications/ Precautions Contraindications: Pt's that don't have CCR5-tropic HIV 1, Current findings of hepatitis, Allergy to maraviroc, Pt's beginning first treatment Precautions: Liver or renal impairment, cardiac disease, older adults
Maraviroc: Interactions Protease inhibitors and delavirdine raise maraviroc levels. Rifampin, efavirenz, phenytoin, and St. John's wort decrease maraviroc levels
Created by: Jeurden
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