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Syphilis
| Question | Answer |
|---|---|
| Syphillis is caused by a cork screw bacteria called...... | Treponema pallidum |
| True or false: syphillis stains silver | true |
| can syphillis be grown in vitro? | no |
| Can Syphillis mutate | no, its genome its conserved and stable. Susceptible to penicillin |
| True or False: T pallidum is destroyed easily | true; a variety of physical and chemical agents like soap and water |
| Describe the pathology | t palliudum enters through abrasions or through unbroken skin by hair follicles |
| If the circulatory system is attacked by the bactera what happens? | it affects the lymphatic system and bloodstream |
| Describe primary syphillis stage | spirochetal load increases and forms a chancre at inoculation site |
| true or false: Chancre lesions may not develop in every case. They are highly infectious. | Both statements are true |
| Describe each primary stage | Red, painless papule Base of the chancre is smooth but the borders are raised and indurated Ulceration occurs with exudate present when secondarily infected Crusts over and heals spontaneously, disappearing within a few weeks |
| What are the dental implications | lips, tongue, oral mucosa |
| Describe secondary syphilis | after the chancre has formed (2-8 weeks) may or may not still be present. Spirochetal load at its peak. Flu like symptoms. Skin rash on face, feet, hands. Mucous patch appears. |
| Describe a mucous patch and where it occurs | A painless shallow ulcer that forms on the lips, soft palate, tongue. Its grayish white red looking. |
| Alopecia occurs in Secondary syphilis | |
| Describe latent syphilis | Begins when the symptom of secondary disappears. It is only detectable by blood work. |
| Describe Early Latent syphilis | clinical symptoms appear during the 1st year |
| Describe Late Latent Syphilis | Bacteria is destroying the internal organs inside but there is no symptoms on the outside |
| Describe tertiary latent syphiliis | destructive stage of the disease. Sub divided into neuro, cardiovascular, gummatous. |
| Describe gumma | a granuloma lesion on the skin and bones. Responds dramatically to antimicrobial therapy. Develops after 5-30 yrs after infection of 15% of untreated infections. |
| Describe neurosyphilis | invasion of the CNS in early syphilis. symptoms dont show until 5-10 yrs |
| What percentage of tertiary syphillis neurosyphilis occur | 8% of untreated cases |
| What are major clinical signs of tertiary syphilis | -paresis: paralysis -Tabes Dorsalis: intense pains, incoordination, functional disturbances of most organs -Personality changes |
| Describe Cardiovascular | aoritis- the elastic tissue of the aorta is replaced by fibrous tissue |
| Describe complications of aoritis | aortic regurgitation obstruction of the coronary arteries aortic aneurysm aortic valve incompetence |
| Prenatal Syphilis | among those who survive infancy, 40% develop late symptoms of syphilis |
| describe prenatal syphilis | Cutaneous lesions much like secondary syphilis in the adult. |
| describe late prenatal syphilis | Hutchinson incisors and first molars with defective and/or supernumerary cusps |
| When diagnosed and treated in its early stages, syphilis is easy to cure. | |
| What is the treatment for symphilis | penicillin g given parenterally. A single injection of penicillin can stop the disease from progressing if you've been infected for less than a year. If you've had syphilis for longer than a year, you may need additional doses. |
Created by:
DH_Student